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| <small>'''''Synonyms:''''' Ciprofloxacin monohydrochloride, Ciprofloxacin hydrochloride, Ciprofloxacin HCl, Ciprofloxacin dihydrochloride, Ciprofloxacina</small>
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| | {{Ciprofloxacin}} |
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| <small>'''''Brand Names:''''' Bacquinor, Baycip, Bernoflox, Ciflox, Cifloxin, Ciloxan, Ciprinol, Cipro, Cipro I.V., Cipro XL, Cipro XR, Ciprobay, Ciprocinol, Ciprodar, Cipromycin, Ciproquinol, Ciproxan, Ciproxin, Flociprin, Floxin, Ocuflox, Proquin XR, Septicide, Velomonit</small>
| | ==Overview== |
| | Ciprofloxacin (INN) is a second-generation [[fluoroquinolone]] antibiotic.[2][3] Its spectrum of activity includes most strains of bacterial pathogens responsible for respiratory, urinary tract, gastrointestinal, and abdominal infections.Ciprofloxacin is used alone or in combination with other antibacterial drugs in the empiric treatment of infections for which the bacterial pathogen has not been identified.It is used as tablet, film coated, oral suspension , eye drops or solution. |
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| | ==Category== |
| | [[fluoroquinolone]], second generation. |
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| ==Dosing and Administration== | | ==US Brand Names== |
| '''Adults''': The determination of dosage for any particular patient must take into consideration the severity and nature of the infection, the susceptibility of the causative organism, the integrity of the patient's host-defense mechanisms, and the status of renal function and hepatic function.
| | CETRAXAL<sup>®</sup>, CILOXN<sup>®</sup>,CIPRO<sup>®</sup> . |
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| '''Children''': Dosing and initial route of therapy (i.e., I.V. or oral) for complicated urinary tract infection or pyelonephritis should be determined by the severity of the infection. In the clinical trial, pediatric patients with moderate to severe infection were initiated on 6 to 10 mg/kg I.V. every 8 hours and allowed to switch to oral therapy (10 to 20 mg/kg every 12 hours), at the discretion of the physician.
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| [[{{PAGENAME}}#FDA Package Insert Resources|FDA Package Insert Resources]]
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| <br></font size><small>Indications, Contraindications, Side Effects, Drug Interactions, etc.</small><font size="4"><br>
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| [http://www.pace-med-apps.com/gfrcalc.htm Calculate Creatine Clearance]
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| <br></font size><small>On line calculator of your patients Cr Cl by a variety of formulas.</small><font size="4"><br>
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| [http://home.earthlink.net/~sensei11/convert.htm Convert pounds to Kilograms]
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| <br></font size><small>On line calculator of your patients weight in pounds to Kg for dosing estimates.</small><font size="4"><br>
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| <br> [[{{PAGENAME}}#Publication Resources|Publication Resources]]
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| <br></font size><small>Recent articles, WikiDoc State of the Art Review, Textbook Information</small><font size="4"><br>
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| [[{{PAGENAME}}#Trial Resources|Trial Resources]]
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| <br></font size><small>Ongoing Trials, Trial Results</small><font size="4"><br>
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| [[{{PAGENAME}}#Guidelines & Evidence Based Medicine Resources|Guidelines & Evidence Based Medicine Resources]]
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| <br></font size><small>US National Guidelines, Cochrane Collaboration, etc.</small><font size="4"><br>
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| [[{{PAGENAME}}#Media Resources|Media Resources]]
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| <br></font size><small>Slides, Video, Images, MP3, Podcasts, etc.</small><font size="4"><br><br> | |
| [[{{PAGENAME}}#Patient Resources|Patient Resources]]
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| <br></font size><small>Discussion Groups, Handouts, Blogs, News, etc.</small><font size="4"><br> | |
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| [[{{PAGENAME}}#International Resources|International Resources]]
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| <br></font size><small>en Español</small><font size="4"><br>
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| ==FDA Package Insert Resources== | | ==FDA Package Insert== |
| [[{{PAGENAME}} indications|Indications]] | | ''' [[Ciprofloxacin description|Description]]''' |
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| | '''| [[Ciprofloxacin clinical pharmacology|Clinical Pharmacology]]''' |
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| | '''| [[Ciprofloxacin microbiology|Microbiology]]''' |
| [[{{PAGENAME}} contraindications|Contraindications]] | | '''| [[Ciprofloxacin indications and usage|Indications and Usage]]''' |
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| | '''| [[Ciprofloxacin contraindications|Contraindications]]''' |
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| | '''| [[Ciprofloxacin warnings|Warnings]]''' |
| [[{{PAGENAME}} side effects|Side Effects]] | | '''| [[Ciprofloxacin precautions|Precautions]]''' |
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| | '''| [[Ciprofloxacin adverse reactions|Adverse Reactions]]''' |
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| | '''| [[Ciprofloxacin overdosage|Overdosage]]''' |
| [[{{PAGENAME}} drug interactions|Drug Interactions]] | | '''| [[Ciprofloxacin clinical studies|Clinical Studies]]''' |
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| | '''| [[Ciprofloxacin dosage and administration|Dosage and Administration]]''' |
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| | '''| [[Ciprofloxacin how supplied|How Supplied]]''' |
| [[{{PAGENAME}} precautions|Precautions]] | | '''| [[Ciprofloxacin labels and packages|Labels and Packages]]''' |
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| [[{{PAGENAME}} overdose|Overdose]] | |
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| [[{{PAGENAME}} instructions for administration|Instructions for Administration]] | |
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| [[{{PAGENAME}} how supplied|How Supplied]] | |
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| [[{{PAGENAME}} pharmacokinetics and molecular data|Pharmacokinetics and Molecular Data]] | |
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| [http://www.fda.gov/cder/foi/label/2000/20780S08lbl.pdf FDA label] | |
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| [http://google2.fda.gov/search?q={{urlencode:{{#if:{{{1|}}}|{{{1}}}|{{PAGENAME}}}}}}&x=0&y=0&client=FDA&site=FDA&lr=&proxystylesheet=FDA&output=xml_no_dtd&getfields=* FDA on {{PAGENAME}}] | |
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| ==Publication Resources== | | ==References== |
| [http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?CMD=search&db=pubmed&term={{urlencode:{{#if:{{{1|}}}|{{{1}}}|{{PAGENAME}}}}}} Most Recent Articles on {{#if:{{{1|}}}|{{{1}}}|{{PAGENAME}}}}]
| | {{Reflist|2}} |
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| | http://www.accessdata.fda.gov/drugsatfda_docs/label/2011/019537s075,020780s033lbl.pdf |
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| | [[Category:Antibiotics]] |
| [http://www.ncbi.nlm.nih.gov/sites/entrez?cmd=search&db=pubmed&term={{urlencode:{{#if:{{{1|}}}|{{{1}}}|{{PAGENAME}}}}}}%20AND%20systematic%5Bsb%5D Review Articles on {{PAGENAME}}]
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| [http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&db=pubmed&term={{urlencode:{{#if:{{{1|}}}|{{{1}}}|{{PAGENAME}}}}}}+AND+%28%28N+Engl+J+Med%5Bta%5D%29+OR+%28Lancet%5Bta%5D%29+OR+%28BMJ%5Bta%5D%29%29 Articles on {{PAGENAME}} in N Eng J Med, Lancet, BMJ]
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| [[WikiDoc state of the art review on {{PAGENAME}}|WikiDoc State of the Art Review]]
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| [http://books.google.com/books?ie=UTF-8&oe=utf-8&q={{urlencode:{{#if:{{{1|}}}|{{{1}}}|{{PAGENAME}}}}}}&qt_s=Search&sa=N&tab=gp Textbook Information on {{PAGENAME}}]
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| ==Trial Resources==
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| [http://clinicaltrials.gov/search/open/condition={{urlencode:{{#if:{{{1|}}}|{{{1}}}|{{PAGENAME}}}}}} Ongoing Trials with {{PAGENAME}} at Clinical Trials.gov]
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| ==Guidelines & Evidence Based Medicine Resources==
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| [http://www.guideline.gov/search/searchresults.aspx?Type=3&txtSearch={{urlencode:{{#if:{{{1|}}}|{{{1}}}|{{PAGENAME}}}}}}&num=20 US National Guidelines Clearinghouse on {{PAGENAME}}]
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| [http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=search&db=pubmed&term={{urlencode:({{#if:{{{1|}}}|{{{1}}}|{{PAGENAME}}}}) AND (Cochrane Database Syst Rev[ta])}} Cochrane Collaboration on {{PAGENAME}}]
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| ==Media Resources==
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| [http://www.google.com/search?q={{urlencode:{{#if:{{{1|}}}|{{{1}}}|{{PAGENAME}}}}}}+ppt&ie=utf-8&oe=utf-8&aq=t&rls=org.mozilla:en-US:official&client=firefox-a Powerpoint Slides on {{PAGENAME}}]
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| [http://www.google.com/search?hl=en&client=firefox-a&rls=org.mozilla%3Aen-US%3Aofficial&hs=hPo&q={{urlencode:{{#if:{{{1|}}}|{{{1}}}|{{PAGENAME}}}}}}+podcasts+OR+MP3&btnG=Search Podcasts & MP3s on {{PAGENAME}}]
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| [http://video.google.com/videosearch?q={{urlencode:{{#if:{{{1|}}}|{{{1}}}|{{PAGENAME}}}}}}&ie=UTF-8&oe=utf-8&rls=org.mozilla:en-US:official&um=1&sa=N&tab=fv# Videos on {{PAGENAME}}]
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| ==Patient Resources==
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| [[{{PAGENAME}} (patient information)|Patient Information from National Library of Medicine]]
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| [http://www.google.com/search?hl=en&q={{urlencode:{{#if:{{{1|}}}|{{{1}}}|{{PAGENAME}}}}}}+more:for_patients&cx=disease_for_patients&sa=N&oi=cooptsr&resnum=0&ct=col3&cd=1 Patient Resources on {{PAGENAME}}]
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| [http://groups.google.com/groups/search?ie=UTF-8&oe=utf-8&q={{urlencode:{{#if:{{{1|}}}|{{{1}}}|{{PAGENAME}}}}}}&qt_s=Search Discussion Groups on {{PAGENAME}}]
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| [http://blogsearch.google.com/blogsearch?q={{urlencode:{{#if:{{{1|}}}|{{{1}}}|{{PAGENAME}}}}}}&ie=UTF-8&oe=utf-8&rls=org.mozilla:en-US:official&client=firefox-a&um=1&sa=N&tab=wb Blogs on {{PAGENAME}}]
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| [http://finance.google.com/finance?ie=UTF-8&oe=utf-8&q={{urlencode:{{#if:{{{1|}}}|{{{1}}}|{{PAGENAME}}}}}}&qt_s=Search&sa=N&tab=te {{PAGENAME}} in the Marketplace]
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| ==International Resources==
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| [http://www.google.com/search?q={{urlencode:{{#if:{{{1|}}}|{{{1}}}|{{PAGENAME}}}}}}+en+espanol&ie=utf-8&oe=utf-8&aq=t&rls=org.mozilla:en-US:official&client=firefox-a {{PAGENAME}} en Español]
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| {{FDA}}
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| [[Category:Drugs]] | |