Amyl nitrite warnings and precautions: Difference between revisions
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==Precautions== | ==Precautions== | ||
Amyl nitrite is very flammable. Do not use where it might become ignited. General - Tolerance to amyl nitrite may develop with repeated use of the drug for prolonged periods of time. Tolerance may be minimized by beginning with the smallest effective dose and alternating the drug with another coronary [[vasodilator]]. High doses of nitrites may produce [[methemoglobinemia]], especially in individuals with methemoglobin reductase deficiency or other metabolic abnormality that interferes with the normal conversion of methemoglobin back to hemoglobin.<ref name="dailymed.nlm.nih.gov">{{Cite web | last = | first = | title = AMYL NITRITE INHALANT [JAMES ALEXANDER CORPORATION] | url = http://dailymed.nlm.nih.gov/dailymed/lookup.cfm?setid=c1b6e536-df5f-4f76-8e3c-6dc2f1e9975e | publisher = | date = | accessdate = 30 January 2014 }}</ref> | Amyl nitrite is very flammable. Do not use where it might become ignited. General - Tolerance to amyl nitrite may develop with repeated use of the drug for prolonged periods of time. Tolerance may be minimized by beginning with the smallest effective dose and alternating the drug with another coronary [[vasodilator]]. High doses of nitrites may produce [[methemoglobinemia]], especially in individuals with methemoglobin reductase deficiency or other metabolic abnormality that interferes with the normal conversion of [[methemoglobin]] back to [[hemoglobin]].<ref name="dailymed.nlm.nih.gov">{{Cite web | last = | first = | title = AMYL NITRITE INHALANT [JAMES ALEXANDER CORPORATION] | url = http://dailymed.nlm.nih.gov/dailymed/lookup.cfm?setid=c1b6e536-df5f-4f76-8e3c-6dc2f1e9975e | publisher = | date = | accessdate = 30 January 2014 }}</ref> | ||
==References== | ==References== | ||
Revision as of 23:37, 30 January 2014
| Amyl nitrite |
|---|
| Amyl nitrite tablet® FDA Package Insert |
| Indications and Usage |
| Dosage and Administration |
| Contraindications |
| Warnings and Precautions |
| Adverse Reactions |
| Drug Interactions |
| Overdosage |
| Description |
| Clinical Pharmacology |
| How Supplied/Storage and Handling |
| Patient Counseling Information |
| Labels and Packages |
| Clinical Trials |
| ClinicalTrials.gov |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Pratik Bahekar, MBBS [2]
Warnings
Transient episodes of dizziness, weakness, or syncope or other signs of cerebral ischemia due to postural hypotension may develop following inhalation of amyl nitrite, particularly if the patient is standing immobile. To hasten recovery, measures which facilitate venous return such as head low posture, deep breathing and movement of extremities may be used.
Precautions
Amyl nitrite is very flammable. Do not use where it might become ignited. General - Tolerance to amyl nitrite may develop with repeated use of the drug for prolonged periods of time. Tolerance may be minimized by beginning with the smallest effective dose and alternating the drug with another coronary vasodilator. High doses of nitrites may produce methemoglobinemia, especially in individuals with methemoglobin reductase deficiency or other metabolic abnormality that interferes with the normal conversion of methemoglobin back to hemoglobin.[1]
References
- ↑ "AMYL NITRITE INHALANT [JAMES ALEXANDER CORPORATION]". Retrieved 30 January 2014.