Amyl nitrite contraindications: Difference between revisions
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==Contraindications== | ==Contraindications== | ||
Since it may increase intraocular and intracranial pressures, amyl nitrite is contraindicated or should be used with great caution in patients with [[glaucoma]], recent [[head trauma]] or [[cerebral hemorrhage]]. Amyl nitrite can cause harm to the fetus when it is administered to a pregnant woman because it significantly reduces systemic blood pressure and blood flow on the maternal side of the placenta.<ref name="dailymed.nlm.nih.gov">{{Cite web | last = | first = | title = AMYL NITRITE INHALANT [JAMES ALEXANDER CORPORATION] | url = http://dailymed.nlm.nih.gov/dailymed/lookup.cfm?setid=c1b6e536-df5f-4f76-8e3c-6dc2f1e9975e | publisher = | date = | accessdate = 30 January 2014 }}</ref> | Since it may increase intraocular and intracranial pressures, amyl nitrite is contraindicated or should be used with great caution in patients with [[glaucoma]], recent [[head trauma]] or [[cerebral hemorrhage]]. Amyl nitrite can cause harm to the fetus when it is administered to a pregnant woman because it significantly reduces systemic blood pressure and blood flow on the maternal side of the placenta. | ||
===Carcinogenesis, Mutagenesis, Fertility Impairment=== | |||
Adequate long term studies to establish adverse carcinogenic potential of this drug have not been reported. | |||
===Pregnancy=== | |||
Teratogenic effects. Category C. Animal studies have not been conducted with amyl nitrite. It is also not known whether amyl nitrite can cause fetal harm when administered to a pregnant woman or can affect reproduction capacity. Amyl nitrite should be given to a pregnant woman only if clearly needed. | |||
===Nursing Mothers=== | |||
It is not known whether this drug is excreted in human milk. Because many drugs are excreted in human milk, caution should be exercised when amyl nitrite is administered to a nursing woman. | |||
===Pediatric Use=== | |||
Safety and effectiveness in children have not been established.<ref name="dailymed.nlm.nih.gov">{{Cite web | last = | first = | title = AMYL NITRITE INHALANT [JAMES ALEXANDER CORPORATION] | url = http://dailymed.nlm.nih.gov/dailymed/lookup.cfm?setid=c1b6e536-df5f-4f76-8e3c-6dc2f1e9975e | publisher = | date = | accessdate = 30 January 2014 }}</ref> | |||
==References== | ==References== | ||
Revision as of 23:55, 30 January 2014
| Amyl nitrite |
|---|
| Amyl nitrite tablet® FDA Package Insert |
| Indications and Usage |
| Dosage and Administration |
| Contraindications |
| Warnings and Precautions |
| Adverse Reactions |
| Drug Interactions |
| Overdosage |
| Description |
| Clinical Pharmacology |
| How Supplied/Storage and Handling |
| Patient Counseling Information |
| Labels and Packages |
| Clinical Trials |
| ClinicalTrials.gov |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Pratik Bahekar, MBBS [2]
Contraindications
Since it may increase intraocular and intracranial pressures, amyl nitrite is contraindicated or should be used with great caution in patients with glaucoma, recent head trauma or cerebral hemorrhage. Amyl nitrite can cause harm to the fetus when it is administered to a pregnant woman because it significantly reduces systemic blood pressure and blood flow on the maternal side of the placenta.
Carcinogenesis, Mutagenesis, Fertility Impairment
Adequate long term studies to establish adverse carcinogenic potential of this drug have not been reported.
Pregnancy
Teratogenic effects. Category C. Animal studies have not been conducted with amyl nitrite. It is also not known whether amyl nitrite can cause fetal harm when administered to a pregnant woman or can affect reproduction capacity. Amyl nitrite should be given to a pregnant woman only if clearly needed.
Nursing Mothers
It is not known whether this drug is excreted in human milk. Because many drugs are excreted in human milk, caution should be exercised when amyl nitrite is administered to a nursing woman.
Pediatric Use
Safety and effectiveness in children have not been established.[1]
References
- ↑ "AMYL NITRITE INHALANT [JAMES ALEXANDER CORPORATION]". Retrieved 30 January 2014.