Acute tubular necrosis causes: Difference between revisions
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==Overview== | ==Overview== | ||
==Causes== | ==Causes== | ||
=== | ===Ischemic Acute Tubular Necrosis=== | ||
Renal hypoperfusion is the major cause of ischemic ATN. A decrease in blood pressure to the extent that renal protective mechanisms fail to maintain adequate perfusion leads to ATP depletion and cell necrosis. Some etiologies associated with ischemic ATN include: | |||
* Hypotension | |||
* Sepsis | |||
* Cardiogenic shock | |||
* Renal vein thrombosis | |||
* ACE inhibitors | |||
* Angiotensin receptor blockers | |||
* NSAIDs | |||
==References== | ==References== | ||
{{reflist|2}} | {{reflist|2}} |
Revision as of 19:36, 1 February 2014
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor-In-Chief: Cafer Zorkun, M.D., Ph.D. [2]
Overview
Causes
Ischemic Acute Tubular Necrosis
Renal hypoperfusion is the major cause of ischemic ATN. A decrease in blood pressure to the extent that renal protective mechanisms fail to maintain adequate perfusion leads to ATP depletion and cell necrosis. Some etiologies associated with ischemic ATN include:
- Hypotension
- Sepsis
- Cardiogenic shock
- Renal vein thrombosis
- ACE inhibitors
- Angiotensin receptor blockers
- NSAIDs