Almotriptan: Difference between revisions

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m (Changed protection level for "Almotriptan" ([Edit=Allow only autoconfirmed users] (expires 20:49, 17 February 2014 (UTC)) [Move=Allow only autoconfirmed users] (expires 20:49, 17 February 2014 (UTC))))
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{{drugbox
__NOTOC__
| IUPAC_name = N,N-dimethyl-2- [5-(pyrrolidin-1-ylsulfonylmethyl)- 1H-indol-3-yl]-ethanamine
{{Almotriptan}}
| image = Almatriptan.svg
{{CMG}}; {{AE}}
| width = 250px
| CAS_number = 154323-57-6
| ATC_prefix = N02
| ATC_suffix = CC05
| ATC_supplemental =
| PubChem = 123606
| DrugBank = APRD00169
| C=17 | H=25 | N=3 | O=2 | S=1
| molecular_weight = 335.465 g/mol
| bioavailability = 70%
| protein_bound = 35%
| metabolism =
| elimination_half-life = 3-4 hours
| pregnancy_category = C(USA)
| legal_status = [[Prescription drug|Prescription only]]
| routes_of_administration =[[Mouth|Oral]]
}}
'''Almotriptan''' ('''Axert®''', '''Almogran®''') is a [[triptan]] [[medication|drug]] discovered by [[Almirall Prodesfarma]] and licensed to [[Ortho-McNeil]] for the treatment of [[migraine]] [[headache]]s.  It is available in strengths of 6.25 and 12.5 mg as a tablet.


In the [[United States]] and [[Canada]] almotriptan is available under the name Axert® only by [[Medical prescription|prescription]]. AXERT® for oral administration contains almotriptan malate equivalent to 6.25 or 12.5 mg of almotriptan. Each compressed tablet contains the following inactive ingredients: mannitol, cellulose, povidone, sodium starch glycolate, sodium stearyl fumarate, titanium dioxide, hypromellose, polyethylene glycol, propylene glycol, iron oxide (6.25 mg only), FD&C Blue No. 2 (12.5 mg only), and carnauba wax.
'''''For patient information about Almotriptan, click [[Almotriptan (patient information)|here]]'''''
The brand Almogran is used in [[Belgium]], [[Finland]], [[France]], [[Germany]], [[Italy]], [[Portugal]], [[Spain]] and the [[United Kingdom]]. Each 12.5 mg. tablet contains the following inactiva ingredients: carnauba wax, hypromellose, indigo carmine (E132), macrogol 400, mannitol,
microcrystalline cellulose, povidone, propylene glycol, sodium starch glycollate, sodium stearyl fumarate and titanium dioxide (E171).


<br style="clear: both;" />
{{SB}}


==External links==
==Overview==
*[http://www.almirall.es/almirall/cda/nav_eng/03/0303.jsp R&D page] by Almirall Prodesfarma
*[http://www.axert.com Axert] Official homepage by Ortho-McNeil


{{triptans}}
==Category==


[[Category:Triptans]]
==FDA Package Insert==


'''| [[Almotriptan indications and usage|Indications and Usage]]'''
'''| [[Almotriptan dosage and administration|Dosage and Administration]]'''
'''| [[Almotriptan dosage forms and strengths|Dosage Forms and Strengths]]'''
'''| [[Almotriptan contraindications|Contraindications]]'''
'''| [[Almotriptan warnings and precautions|Warnings and Precautions]]'''
'''| [[Almotriptan adverse reactions|Adverse Reactions]]'''
'''| [[Almotriptan drug interactions|Drug Interactions]]'''
'''| [[Almotriptan use in specific populations|Use in Specific Populations]]'''
'''| [[Almotriptan overdosage|Overdosage]]'''
'''| [[Almotriptan description|Description]]'''
'''| [[Almotriptan clinical pharmacology|Clinical Pharmacology]]'''
'''| [[Almotriptan nonclinical toxicology|Nonclinical Toxicology]]'''
'''| [[Almotriptan clinical studies|Clinical Studies]]'''
'''| [[Almotriptan how supplied storage and handling|How Supplied/Storage and Handling]]'''
'''| [[Almotriptan patient counseling information|Patient Counseling Information]]'''
'''| [[Almotriptan labels and packages|Labels and Packages]]'''


{{pharma-stub}}
==Mechanism of Action==


[[de:Almotriptan]]
==References==
[[es:Almotriptán]]
 
{{Reflist|2}}
 
[[Category:Cardiovascular Drugs]]
[[Category:Drugs]]

Revision as of 01:33, 5 February 2014