Sandbox: Difference between revisions

Revision as of 16:37, 6 February 2014

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Rim Halaby, M.D. [2]

Sepsis is a life threatening condition.^[1]^[2]

↑ XYZ, NEJM, 2014
↑ Remick DG (2007). "Pathophysiology of sepsis". Am J Pathol. 170 (5): 1435–44. doi:10.2353/ajpath.2007.060872. PMC 1854939. PMID 17456750.CS1 maint: PMC format (link)

Common Causes of DIC

Infections:
- Sepsis, particularly with gram-negative bacteria
- Viral
- Malaria
- Rickettsial
Obstetric complications (most common cause), with chemicals from the uterus being released into the blood. These include:
- Amniotic fluid embolism
- Eclampsia
- Abruptio placentae
- Placenta praevia
- intra-uterine death
Tissue trauma such as burns, accidents, surgery, heat stroke or shock.
Liver disease:
- Cirrhosis
- Acute hepatic necrosis
Incompatible blood transfusion reactions or massive blood transfusion (when more than the total circulatory volume is tranfused)
Graft-versus-host disease
Cancers, particularly of the following types, and especially when metastatic:
- Stomach cancer
- Colorectal cancer
- Pancreatic cancer
- Mucin-secreting adenocarcinoma
- Acute promyelocytic leukemia
Viral hemorrhagic fevers bring about their frank effects, paradoxically, by causing DIC.
Envenomation by some species of venomous snakes, such as those belonging to the genus Echis (saw-scaled vipers).

@@ Line 9: / Line 9: @@
 ==References==
 {{Reflist|2}}
+Common Causes of DIC
+* Infections:
+** [[Sepsis]], particularly with [[gram-negative bacteria]]
+** Viral
+** [[Malaria]]
+** [[Rickettsial]]
+* Obstetric complications (most common cause), with chemicals from the [[uterus]] being released into the blood. These include:
+** [[Amniotic fluid embolism]]
+** [[Eclampsia]]
+** ''[[Abruptio placentae]]''
+** [[Placenta praevia]]
+** intra-uterine death
+* Tissue trauma such as burns, accidents, surgery, heat stroke or [[Shock (medical)|shock]].
+* [[Liver]] disease:
+** [[Cirrhosis]]
+** Acute hepatic [[necrosis]]
+* Incompatible blood [[transfusion reaction]]s or massive [[blood transfusion]] (when more than the total circulatory volume is tranfused)
+* [[Graft-versus-host disease]]
+* Cancers, particularly of the following types, and especially when [[metastatic]]:
+** [[Stomach cancer]]
+** [[Colorectal cancer]]
+** [[Pancreatic cancer]]
+** [[Mucin]]-secreting [[adenocarcinoma]]
+** [[Acute promyelocytic leukemia]]
+* [[Viral hemorrhagic fever]]s bring about their frank effects, paradoxically, by causing DIC.
+* Envenomation by some [[species]] of [[venomous snake]]s, such as those belonging to the [[genus]] ''[[Echis]]'' (saw-scaled vipers).