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Common Causes of DIC | ==Common Causes of DIC== | ||
* Infections: | * Infections: | ||
** [[Sepsis]], particularly with [[gram-negative bacteria]] | ** [[Sepsis]], particularly with [[gram-negative bacteria]] |
Revision as of 16:38, 6 February 2014
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Rim Halaby, M.D. [2]
Overview
Sepsis is a life threatening condition.[1][2]
Title
References
- ↑ XYZ, NEJM, 2014
- ↑ Remick DG (2007). "Pathophysiology of sepsis". Am J Pathol. 170 (5): 1435–44. doi:10.2353/ajpath.2007.060872. PMC 1854939. PMID 17456750.
Common Causes of DIC
- Infections:
- Sepsis, particularly with gram-negative bacteria
- Viral
- Malaria
- Rickettsial
- Obstetric complications (most common cause), with chemicals from the uterus being released into the blood. These include:
- Amniotic fluid embolism
- Eclampsia
- Abruptio placentae
- Placenta praevia
- intra-uterine death
- Tissue trauma such as burns, accidents, surgery, heat stroke or shock.
- Liver disease:
- Incompatible blood transfusion reactions or massive blood transfusion (when more than the total circulatory volume is tranfused)
- Graft-versus-host disease
- Cancers, particularly of the following types, and especially when metastatic:
- Viral hemorrhagic fevers bring about their frank effects, paradoxically, by causing DIC.
- Envenomation by some species of venomous snakes, such as those belonging to the genus Echis (saw-scaled vipers).