Frovatriptan drug interactions: Difference between revisions

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==Drug Interactions==
==Drug Interactions==
<div>===Ergot-containing Drugs===
===Ergot-containing Drugs===


Ergot-containing drugs have been reported to cause prolonged vasospastic reactions. Because these effects may be additive, use of ergotamine-containing or ergot-type medications (like [[dihydroergotamine]] or [[methysergide]]) and FROVA within 24 hours of each other is contraindicated [see Contraindications (4)].
Ergot-containing drugs have been reported to cause prolonged vasospastic reactions. Because these effects may be additive, use of ergotamine-containing or ergot-type medications (like [[dihydroergotamine]] or [[methysergide]]) and FROVA within 24 hours of each other is contraindicated [see Contraindications (4)].
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===Selective [[Serotonin]] Reuptake Inhibitors / [[Serotonin]] [[Norepinephrine]] Reuptake Inhibitors and [[Serotonin]] Syndrome===
===Selective [[Serotonin]] Reuptake Inhibitors / [[Serotonin]] [[Norepinephrine]] Reuptake Inhibitors and [[Serotonin]] Syndrome===


Cases of [[Serotonin]] syndrome have been reported during combined use of triptans and [[SSRIs]], [[SNRI]]s, TCAs, and [[MAO]] inhibitors [see Warnings and Precautions (5.7)].<ref name="dailymed.nlm.nih.gov">{{Cite web  | last =  | first =  | title = FROVA (FROVATRIPTAN SUCCINATE) TABLET, FILM COATED [ENDO PHARMACEUTICALS INC.] | url = http://dailymed.nlm.nih.gov/dailymed/lookup.cfm?setid=c0703630-9ce8-4259-841e-71fd2019fa66 | publisher =  | date =  | accessdate = 7 February 2014 }}</ref></div>
Cases of [[Serotonin]] syndrome have been reported during combined use of triptans and [[SSRIs]], [[SNRI]]s, TCAs, and [[MAO]] inhibitors [see Warnings and Precautions (5.7)].<ref name="dailymed.nlm.nih.gov">{{Cite web  | last =  | first =  | title = FROVA (FROVATRIPTAN SUCCINATE) TABLET, FILM COATED [ENDO PHARMACEUTICALS INC.] | url = http://dailymed.nlm.nih.gov/dailymed/lookup.cfm?setid=c0703630-9ce8-4259-841e-71fd2019fa66 | publisher =  | date =  | accessdate = 7 February 2014 }}</ref>


==References==
==References==

Revision as of 17:25, 7 February 2014

Frovatriptan
FROVA® FDA Package Insert
Indications and Usage
Dosage and Administration
Dosage Forms and Strengths
Contraindications
Warnings and Precautions
Adverse Reactions
Drug Interactions
Use in Specific Populations
Overdosage
Description
Clinical Pharmacology
Nonclinical Toxicology
Clinical Studies
How Supplied/Storage and Handling
Patient Counseling Information
Labels and Packages
Clinical Trials on Frovatriptan
ClinicalTrials.gov

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Sheng Shi, M.D. [2]

Drug Interactions

Ergot-containing Drugs

Ergot-containing drugs have been reported to cause prolonged vasospastic reactions. Because these effects may be additive, use of ergotamine-containing or ergot-type medications (like dihydroergotamine or methysergide) and FROVA within 24 hours of each other is contraindicated [see Contraindications (4)].

HT1B/1D Agonists

Because their vasospastic effects may be additive, co-administration of FROVA and other 5-HT1 agonists (e.g., triptans) within 24 hours of each other is contraindicated [see Contraindications (4)].

Selective Serotonin Reuptake Inhibitors / Serotonin Norepinephrine Reuptake Inhibitors and Serotonin Syndrome

Cases of Serotonin syndrome have been reported during combined use of triptans and SSRIs, SNRIs, TCAs, and MAO inhibitors [see Warnings and Precautions (5.7)].[1]

References

  1. "FROVA (FROVATRIPTAN SUCCINATE) TABLET, FILM COATED [ENDO PHARMACEUTICALS INC.]". Retrieved 7 February 2014.

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