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{{drugbox
 
| IUPAC_name = [4-[2-hydroxy-3-(1-methylethylamino) propoxy]- 2,3,6-trimethyl-phenyl] ethanoate
{{Drugbox
| image = Metipranolol.png
| verifiedrevid = 411547542
| IUPAC_name = (''RS'')-4-{[-2-hydroxy-3-(isopropylamino)propyl]oxy}-2,3,6-trimethylphenyl acetate
| image = Metipranolol.svg
| width = 200
| imagename = 1 : 1 mixture (racemate)
| drug_name = Metipranolol
 
<!--Clinical data-->
| tradename = Optipranolol
| Drugs.com = {{drugs.com|CONS|metipranolol}}
| MedlinePlus = a601078
| pregnancy_category =
| legal_status =
| routes_of_administration =
 
<!--Pharmacokinetic data-->
| bioavailability =
| protein_bound =
| metabolism =
| elimination_half-life =
 
<!--Identifiers-->
| CASNo_Ref = {{cascite|correct|CAS}}
| CAS_number = 22664-55-7
| CAS_number = 22664-55-7
| ATC_prefix = S01
| ATC_prefix = S01
| ATC_suffix = ED04
| ATC_suffix = ED04
| ATC_supplemental = {{ATC|C07|BA68}}
| ATC_supplemental = {{ATC|C07|BA68}}
| PubChem = 31477
| PubChem = 31477
| DrugBank = APRD00668
| DrugBank_Ref = {{drugbankcite|correct|drugbank}}
| DrugBank = DB01214
| ChemSpiderID_Ref = {{chemspidercite|correct|chemspider}}
| ChemSpiderID = 29193
| UNII_Ref = {{fdacite|correct|FDA}}
| UNII = X39AL81KEB
| KEGG_Ref = {{keggcite|correct|kegg}}
| KEGG = D02374
| ChEMBL_Ref = {{ebicite|correct|EBI}}
| ChEMBL = 1291
 
<!--Chemical data-->
| C=17 | H=27 | N=1 | O=4
| C=17 | H=27 | N=1 | O=4
| molecular_weight = 309.401 g/mol
| molecular_weight = 309.401 g/mol
| bioavailability =  
| smiles = O=C(Oc1c(c(c(OCC(O)CNC(C)C)cc1C)C)C)C
| protein_bound =  
| InChI = 1/C17H27NO4/c1-10(2)18-8-15(20)9-21-16-7-11(3)17(22-14(6)19)13(5)12(16)4/h7,10,15,18,20H,8-9H2,1-6H3
| metabolism =  
| InChIKey = BQIPXWYNLPYNHW-UHFFFAOYAJ
| elimination_half-life =  
| StdInChI_Ref = {{stdinchicite|correct|chemspider}}
| pregnancy_category =  
| StdInChI = 1S/C17H27NO4/c1-10(2)18-8-15(20)9-21-16-7-11(3)17(22-14(6)19)13(5)12(16)4/h7,10,15,18,20H,8-9H2,1-6H3
| legal_status =  
| StdInChIKey_Ref = {{stdinchicite|correct|chemspider}}
| routes_of_administration =  
| StdInChIKey = BQIPXWYNLPYNHW-UHFFFAOYSA-N
}}
}}
__NOTOC__
__NOTOC__{{Metipranolol}}
{{CMG}}
{{CMG}}


{{SB}} METIPRANOLOL


==Overview==


==Overview==
'''Metipranolol hydrochloride''' (OptiPranolol) is a non-selective [[beta blocker]] used in [[eye drop]]s to treat [[glaucoma]].
'''Metipranolol hydrochloride''' (OptiPranolol) is a non-selective [[beta blocker]] used in [[eye drop]]s to treat [[glaucoma]].


==Category==
Beta Blockers
==FDA Package Insert==
====METIPRANOLOL solution/ drops====
'''  [[Metipranolol indications and usage|Indications and Usage]]'''
'''| [[Metipranolol dosage and administration|Dosage and Administration]]'''
'''| [[Metipranolol dosage forms and strengths|Dosage Forms and Strengths]]'''
'''| [[Metipranolol contraindications|Contraindications]]'''
'''| [[Metipranolol warnings and precautions|Warnings and Precautions]]'''
'''| [[Metipranolol adverse reactions|Adverse Reactions]]'''
'''| [[Metipranolol drug interactions|Drug Interactions]]'''
'''| [[Metipranolol use in specific populations|Use in Specific Populations]]'''
'''| [[Metipranolol overdosage|Overdosage]]'''
'''| [[Metipranolol description|Description]]'''
'''| [[Metipranolol clinical pharmacology|Clinical Pharmacology]]'''
'''| [[Metipranolol nonclinical toxicology|Nonclinical Toxicology]]'''
'''| [[Metipranolol clinical studies|Clinical Studies]]'''
'''| [[Metipranolol how supplied storage and handling|How Supplied/Storage and Handling]]'''
'''| [[Metipranolol patient counseling information|Patient Counseling Information]]'''
'''| [[Metipranolol labels and packages|Labels and Packages]]'''
==Mechanism of Action==
Metipranolol blocks beta1 and beta2 (non-selective) adrenergic receptors. It does not have significant intrinsic sympathomimetic activity, and has only weak local anesthetic (membrane-stabilizing) and myocardial depressant activity.
==References==
{{Reflist|2}}


{{beta blockers}}
{{beta blockers}}
{{Antiglaucoma preparations and miotics}}
{{Antiglaucoma preparations and miotics}}


[[Category:Beta blockers]]
[[Category:Beta blockers]]
[[Category:Drugs]]
[[Category:Drugs]]
{{WikiDoc Help Menu}}
{{WikiDoc Sources}}

Revision as of 05:14, 10 February 2014

Metipranolol
File:Metipranolol.svg
Clinical data
Trade namesOptipranolol
AHFS/Drugs.comMicromedex Detailed Consumer Information
MedlinePlusa601078
ATC code
Identifiers
CAS Number
PubChem CID
DrugBank
ChemSpider
UNII
KEGG
ChEMBL
E number{{#property:P628}}
ECHA InfoCard{{#property:P2566}}Lua error in Module:EditAtWikidata at line 36: attempt to index field 'wikibase' (a nil value).
Chemical and physical data
FormulaC17H27NO4
Molar mass309.401 g/mol
3D model (JSmol)
  (verify)
Metipranolol
METIPRANOLOL® FDA Package Insert
Indications and Usage
Dosage and Administration
Contraindications
Warnings and Precautions
Adverse Reactions
Drug Interactions
Use in Specific Populations
Overdosage
Description
Clinical Pharmacology
How Supplied/Storage and Handling
Patient Counseling Information
Labels and Packages
Clinical Trials on Metipranolol
ClinicalTrials.gov

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Synonyms / Brand Names: METIPRANOLOL

Overview

Metipranolol hydrochloride (OptiPranolol) is a non-selective beta blocker used in eye drops to treat glaucoma.

Category

Beta Blockers

FDA Package Insert

METIPRANOLOL solution/ drops

Indications and Usage | Dosage and Administration | Dosage Forms and Strengths | Contraindications | Warnings and Precautions | Adverse Reactions | Drug Interactions | Use in Specific Populations | Overdosage | Description | Clinical Pharmacology | Nonclinical Toxicology | Clinical Studies | How Supplied/Storage and Handling | Patient Counseling Information | Labels and Packages

Mechanism of Action

Metipranolol blocks beta1 and beta2 (non-selective) adrenergic receptors. It does not have significant intrinsic sympathomimetic activity, and has only weak local anesthetic (membrane-stabilizing) and myocardial depressant activity.

References

Template:Antiglaucoma preparations and miotics

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