Dimetotiazine: Difference between revisions

Dimetotiazine
Clinical data
AHFS/Drugs.com	International Drug Names
Pregnancy; category	AU: <! -- A / B1 / B2 / B3 / C / D / X --> ; US: <! -- A / B / C / D / X-- > ; ;
Routes of; administration	Oral
ATC code	N02CX05 (WHO) ;
Legal status
Legal status	AU: <! -- S2, S3, S4, S5, S6, S7, S8, S9 or Unscheduled--> ; CA: <! -- Schedule I, II, III, IV, V, VI, VII, VIII-- > ; UK: <! -- GSL, P, POM, CD, or Class A, B, C-- > ; US: <! -- OTC / Rx-only / Schedule I, II, III, IV, V-- > ; In general: ℞ (Prescription only);
Identifiers
	IUPAC name 10-(2-dimethylaminopropyl)-N,N-dimethylphenothiazine-2-sulfonamide;
CAS Number	7456-24-8 ;
PubChem CID	3089;
ChemSpider	2979 ;
UNII	1FTA475ZDB;
KEGG	D07854 ;
E number	{{#property:P628}}
ECHA InfoCard	{{#property:P2566}}Lua error in Module:EditAtWikidata at line 36: attempt to index field 'wikibase' (a nil value).
Chemical and physical data
Formula	C19H25N3O2S2
Molar mass	391.55 g/mol
3D model (JSmol)	Interactive image;
	SMILES CC(CN1C2=CC=CC=C2SC3=C1C=C(C=C3)S(=O)(=O)N(C)C)N(C)C;
	InChI InChI=1S/C19H25N3O2S2/c1-14(20(2)3)13-22-16-8-6-7-9-18(16)25-19-11-10-15(12-17(19)22)26(23,24)21(4)5/h6-12,14H,13H2,1-5H3 ; Key:VWNWVCJGUMZDIU-UHFFFAOYSA-N ;
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Revision as of 12:24, 10 February 2014

Template:Oxetoron Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Pratik Bahekar, MBBS [2]

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Overview

Dimetotiazine (INN) is a phenothiazine. It is a serotonin antagonist and histamine antagonist.<ref name="pmid8564192">Shimazawa M, Hara H, Watano T, Sukamoto T (August 1995). "Effects of Ca2+ channel blockers on cortical hypoperfusion and expression of c-Fos-like immunoreactivity after cortical spreading depression in rats". Br. J. Pharmacol. 115 (8): 1359–68. PMC 1908864. PMID 8564192.</refIt's chemical name b10H-Phenothiazine-2-sulfonamide, 10-[2-(dimethylamino)propyl]-N,N-dimethyl-

@@ Line 14: / Line 14: @@
 | Drugs.com = {{drugs.com|international|dimetotiazine}}
 | pregnancy_AU =<! -- A / B1 / B2 / B3 / C / D / X -->
-| pregnancy_US =<! -- A / B            / C / D / X -->
+| pregnancy_US =<! -- A / B            / C / D / X-- >
 | pregnancy_category =
 | legal_AU =<! -- S2, S3, S4, S5, S6, S7, S8, S9 or Unscheduled-->
-| legal_CA =<! -- Schedule I, II, III, IV, V, VI, VII, VIII -->
+| legal_CA =<! -- Schedule I, II, III, IV, V, VI, VII, VIII-- >
-| legal_UK =<! -- GSL, P, POM, CD, or Class A, B, C -->
+| legal_UK =<! -- GSL, P, POM, CD, or Class A, B, C-- >
-| legal_US =<! -- OTC / Rx-only / Schedule I, II, III, IV, V -->
+| legal_US =<! -- OTC / Rx-only / Schedule I, II, III, IV, V-- >
 | legal_status = Rx-only
 | routes_of_administration = Oral
@@ Line 62: / Line 62: @@
 ==Overview==
-'''Dimetotiazine''' ([[International Nonproprietary Name|INN]]) is a [[phenothiazine]]. It is a [[serotonin antagonist]] and [[histamine antagonist]].<ref name="pmid8564192">{{cite journal |author=Shimazawa M, Hara H, Watano T, Sukamoto T |title=Effects of Ca2+ channel blockers on cortical hypoperfusion and expression of c-Fos-like immunoreactivity after cortical spreading depression in rats |journal=Br. J. Pharmacol. |volume=115 |issue=8 |pages=1359–68 |date=August 1995 |pmid=8564192 |pmc=1908864 |doi= |url=}}</ref>
+'''Dimetotiazine''' ([[International Nonproprietary Name|INN]]) is a [[phenothiazine]]. It is a [[serotonin antagonist]] and [[histamine antagonist]].<ref name="pmid8564192">{{cite journal |author=Shimazawa M, Hara H, Watano T, Sukamoto T |title=Effects of Ca2+ channel blockers on cortical hypoperfusion and expression of c-Fos-like immunoreactivity after cortical spreading depression in rats |journal=Br. J. Pharmacol. |volume=115 |issue=8 |pages=1359–68 |date=August 1995 |pmid=8564192 |pmc=1908864 |doi= |url=}}</refIt's chemical name b10H-Phenothiazine-2-sulfonamide, 10-[2-(dimethylamino)propyl]-N,N-dimethyl-
 ==Category==

Clinical data

AHFS/Drugs.com	International Drug Names
Pregnancy category	AU: <! -- A / B1 / B2 / B3 / C / D / X --> US: <! -- A / B / C / D / X-- >
Routes of administration	Oral
ATC code	N02CX05 (WHO)
Legal status
Legal status	AU: <! -- S2, S3, S4, S5, S6, S7, S8, S9 or Unscheduled--> CA: <! -- Schedule I, II, III, IV, V, VI, VII, VIII-- > UK: <! -- GSL, P, POM, CD, or Class A, B, C-- > US: <! -- OTC / Rx-only / Schedule I, II, III, IV, V-- > In general: ℞ (Prescription only)
Identifiers
IUPAC name 10-(2-dimethylaminopropyl)-N,N-dimethylphenothiazine-2-sulfonamide
CAS Number	7456-24-8^Y
PubChem CID	3089
ChemSpider	2979^N
UNII	1FTA475ZDB
KEGG	D07854^Y
E number	{{#property:P628}}
ECHA InfoCard	{{#property:P2566}}Lua error in Module:EditAtWikidata at line 36: attempt to index field 'wikibase' (a nil value).
Chemical and physical data
Formula	C₁₉H₂₅N₃O₂S₂
Molar mass	391.55 g/mol
3D model (JSmol)	Interactive image
SMILES CC(CN1C2=CC=CC=C2SC3=C1C=C(C=C3)S(=O)(=O)N(C)C)N(C)C
InChI InChI=1S/C19H25N3O2S2/c1-14(20(2)3)13-22-16-8-6-7-9-18(16)25-19-11-10-15(12-17(19)22)26(23,24)21(4)5/h6-12,14H,13H2,1-5H3^N Key:VWNWVCJGUMZDIU-UHFFFAOYSA-N^N
^NY (what is this?) (verify)

Dimetotiazine: Difference between revisions

Revision as of 12:24, 10 February 2014

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