Constipation pathophysiology: Difference between revisions
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{{Constipation}} | {{Constipation}} | ||
==Overview== | |||
The underlying pathophysiology of constipation involves several processes such as hardening of the stool, paralysis or slow transit, constriction in the lower gastrointestinal system or psychomotor factors. | |||
==Pathophysiology== | |||
* '''Hardening of the feces''': Improper [[mastication]], low [[dietary fiber]], [[dehydration]] and medications ([[aluminium]], [[calcium]], [[diuretic]], [[iron]]). | |||
* '''Paralysis or slowed transit''': [[Hypothyroidism]], [[hypokalemia]], injured [[Anus|anal sphincter]], medications ([[loperamide]], [[codeine]], [[morphine]], [[tricyclic antidepressants]]) and severe systemic illness due to other causes. | |||
* '''Constriction, where part of the intestine or rectum is narrowed or blocked''': [[Diverticulosis]], [[pelvic masses]] and [[stenosis]]. | |||
* '''Psychosomatic constipation''': [[Functional constipation]] and [[irritable bowel syndrome]].<ref>{{cite journal |author=Caldarella MP, Milano A, Laterza F, ''et al'' |title=Visceral sensitivity and symptoms in patients with constipation- or diarrhea-predominant irritable bowel syndrome (IBS): effect of a low-fat intraduodenal infusion |journal=Am. J. Gastroenterol. |volume=100 |issue=2 |pages=383–9 |year=2005 |pmid=15667496 |doi=10.1111/j.1572-0241.2005.40100.x}}</ref> | |||
==References== | ==References== | ||
Revision as of 13:43, 13 February 2014
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Overview
The underlying pathophysiology of constipation involves several processes such as hardening of the stool, paralysis or slow transit, constriction in the lower gastrointestinal system or psychomotor factors.
Pathophysiology
- Hardening of the feces: Improper mastication, low dietary fiber, dehydration and medications (aluminium, calcium, diuretic, iron).
- Paralysis or slowed transit: Hypothyroidism, hypokalemia, injured anal sphincter, medications (loperamide, codeine, morphine, tricyclic antidepressants) and severe systemic illness due to other causes.
- Constriction, where part of the intestine or rectum is narrowed or blocked: Diverticulosis, pelvic masses and stenosis.
- Psychosomatic constipation: Functional constipation and irritable bowel syndrome.[1]
References
- ↑ Caldarella MP, Milano A, Laterza F; et al. (2005). "Visceral sensitivity and symptoms in patients with constipation- or diarrhea-predominant irritable bowel syndrome (IBS): effect of a low-fat intraduodenal infusion". Am. J. Gastroenterol. 100 (2): 383–9. doi:10.1111/j.1572-0241.2005.40100.x. PMID 15667496.