Lisinopril description: Difference between revisions
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==Description== | |||
Lisinopril is an oral long-acting angiotensin converting enzyme inhibitor. Lisinopril, a synthetic peptide derivative, is chemically described as (S)-1-[N2-(1-Carboxy-3-phenyl-propyl)-L-lysyl]-L-proline dihydrate. Its empirical formula is C21H31N3O5·2H2O and its structural formula is: | |||
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<ref name="dailymed.nlm.nih.gov">{{Cite web | last = | first = | title = LISINOPRIL (LISINOPRIL) TABLET [LEK PHARMACEUTICALS] | url = http://dailymed.nlm.nih.gov/dailymed/lookup.cfm?setid=27ccb2f4-abf8-4825-9b05-0bb367b4ac07 | publisher = | date = | accessdate = }}</ref> | Lisinopril is a white to off-white crystalline powder, with a molecular weight of 441.53. It is soluble in water and sparingly soluble in [[methanol]] and practically insoluble in [[ethanol]]. Lisinopril tablets are supplied as 2.5 mg, 5 mg, 10 mg, 20 mg, 30 mg and 40 mg tablets for oral administration. Inactive Ingredients: | ||
2.5 mg tablets - corn starch, croscarmellose sodium, dibasic calcium phosphate, magnesium stearate, mannitol, povidone, pregelatinized starch, titanium dioxide, yellow ferric oxide. | |||
5 mg tablets - black ferric oxide, corn starch, croscarmellose sodium, dibasic calcium phosphate, magnesium stearate, mannitol, povidone, pregelatinized starch, yellow ferric oxide. | |||
10 mg tablets - corn starch, croscarmellose sodium, dibasic calcium phosphate, magnesium stearate, mannitol, povidone, pregelatinized starch, titanium dioxide, yellow ferric oxide. | |||
20 mg tablets - black ferric oxide, corn starch, croscarmellose sodium, dibasic calcium phosphate, magnesium stearate, mannitol, povidone, pregelatinized starch, yellow ferric oxide. | |||
30 mg tablets - black ferric oxide, corn starch, croscarmellose sodium, dibasic calcium phosphate, magnesium stearate, mannitol, povidone, pregelatinized starch, yellow ferric oxide. | |||
40 mg tablets - black ferric oxide, corn starch, croscarmellose sodium, dibasic calcium phosphate, magnesium stearate, mannitol, povidone, pregelatinized starch, yellow ferric oxide.<ref name="dailymed.nlm.nih.gov">{{Cite web | last = | first = | title = LISINOPRIL (LISINOPRIL) TABLET [LEK PHARMACEUTICALS] | url = http://dailymed.nlm.nih.gov/dailymed/lookup.cfm?setid=27ccb2f4-abf8-4825-9b05-0bb367b4ac07 | publisher = | date = | accessdate = }}</ref> | |||
==References== | ==References== | ||
Revision as of 21:46, 13 February 2014
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Ahmed Zaghw, M.D. [2], Amr Marawan, M.D. [3]
Lisinopril
Lisinopril and Hydrochlorothiazide tablet
Overview
Lisinopril tablet is an angiontensin converting enzyme inhibitor drug that is FDA approved for the treatment of hypertension, heart failure, left ventricular dysfunction after myocardial infarction, diabetic nephropathy. Adverse reactions include hypotension, rash, hyperkalemia, disorder of taste, cough. hypotension, rash, hyperkalemia, disorder of taste, cough.
Category
Antihypertensive Agents, Angiotensin Converting Enzyme Inhibitors. Editor-In-Chief: C. Michael Gibson, M.S., M.D. [4]; Associate Editor(s)-in-Chief: Amr Marawan, M.D. [5]
Description
Lisinopril is an oral long-acting angiotensin converting enzyme inhibitor. Lisinopril, a synthetic peptide derivative, is chemically described as (S)-1-[N2-(1-Carboxy-3-phenyl-propyl)-L-lysyl]-L-proline dihydrate. Its empirical formula is C21H31N3O5·2H2O and its structural formula is:
 |
Lisinopril is a white to off-white crystalline powder, with a molecular weight of 441.53. It is soluble in water and sparingly soluble in methanol and practically insoluble in ethanol. Lisinopril tablets are supplied as 2.5 mg, 5 mg, 10 mg, 20 mg, 30 mg and 40 mg tablets for oral administration. Inactive Ingredients:
2.5 mg tablets - corn starch, croscarmellose sodium, dibasic calcium phosphate, magnesium stearate, mannitol, povidone, pregelatinized starch, titanium dioxide, yellow ferric oxide.
5 mg tablets - black ferric oxide, corn starch, croscarmellose sodium, dibasic calcium phosphate, magnesium stearate, mannitol, povidone, pregelatinized starch, yellow ferric oxide.
10 mg tablets - corn starch, croscarmellose sodium, dibasic calcium phosphate, magnesium stearate, mannitol, povidone, pregelatinized starch, titanium dioxide, yellow ferric oxide.
20 mg tablets - black ferric oxide, corn starch, croscarmellose sodium, dibasic calcium phosphate, magnesium stearate, mannitol, povidone, pregelatinized starch, yellow ferric oxide.
30 mg tablets - black ferric oxide, corn starch, croscarmellose sodium, dibasic calcium phosphate, magnesium stearate, mannitol, povidone, pregelatinized starch, yellow ferric oxide.
40 mg tablets - black ferric oxide, corn starch, croscarmellose sodium, dibasic calcium phosphate, magnesium stearate, mannitol, povidone, pregelatinized starch, yellow ferric oxide.[1]
References
Adapted from the FDA Package Insert.