Multiple myeloma other imaging findings: Difference between revisions
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==Overview== | ==Overview== | ||
[[Positron emission tomography]] (PET) scan: When doing this test, a small amount of a radioactive medium is injected into your body and absorbed by the organs or tissues. This [[radioactive]] substance gives off energy which in turn is used to produce the images. PET can provide more helpful information than either CT or MRI scans. It is useful to see if the cancer has spread to the lymph nodes and it is also useful for your doctor to locate where the cancer has spread. | [[Positron emission tomography]] (PET) scan: When doing this test, a small amount of a radioactive medium is injected into your body and absorbed by the organs or tissues. This [[radioactive]] substance gives off energy which in turn is used to produce the images. PET can provide more helpful information than either CT or MRI scans. It is useful to see if the cancer has spread to the lymph nodes and it is also useful for your doctor to locate where the cancer has spread. | ||
PET scan has been shown to be highly sensitive and specific, when combined with MRI it can achieve 100% diagnostic efficacy.<ref name="Shortt-2009">{{Cite journal | last1 = Shortt | first1 = CP. | last2 = Gleeson | first2 = TG. | last3 = Breen | first3 = KA. | last4 = McHugh | first4 = J. | last5 = O'Connell | first5 = MJ. | last6 = O'Gorman | first6 = PJ. | last7 = Eustace | first7 = SJ. | title = Whole-Body MRI versus PET in assessment of multiple myeloma disease activity. | journal = AJR Am J Roentgenol | volume = 192 | issue = 4 | pages = 980-6 | month = Apr | year = 2009 | doi = 10.2214/AJR.08.1633 | PMID = 19304704 }}</ref><ref name="Agarwal-2013">{{Cite journal | last1 = Agarwal | first1 = A. | last2 = Chirindel | first2 = A. | last3 = Shah | first3 = BA. | last4 = Subramaniam | first4 = RM. | title = Evolving role of FDG PET/CT in multiple myeloma imaging and management. | journal = AJR Am J Roentgenol | volume = 200 | issue = 4 | pages = 884-90 | month = Apr | year = 2013 | doi = 10.2214/AJR.12.9653 | PMID = 23521465 }}</ref> The use of PET scan has led to earlier diagnosis of multiple myeloma, more accurate therapy assessment, and better prediction of patient outcome. However, these have not been employed as a standard of care by the International Myeloma Working Group.<ref name="Dimopoulos-2009">{{Cite journal | last1 = Dimopoulos | first1 = M. | last2 = Terpos | first2 = E. | last3 = Comenzo | first3 = RL. | last4 = Tosi | first4 = P. | last5 = Beksac | first5 = M. | last6 = Sezer | first6 = O. | last7 = Siegel | first7 = D. | last8 = Lokhorst | first8 = H. | last9 = Kumar | first9 = S. | title = International myeloma working group consensus statement and guidelines regarding the current role of imaging techniques in the diagnosis and monitoring of multiple Myeloma. | journal = Leukemia | volume = 23 | issue = 9 | pages = 1545-56 | month = Sep | year = 2009 | doi = 10.1038/leu.2009.89 | PMID = 19421229 }}</ref> | |||
==References== | ==References== |
Revision as of 01:33, 18 February 2014
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Overview
Positron emission tomography (PET) scan: When doing this test, a small amount of a radioactive medium is injected into your body and absorbed by the organs or tissues. This radioactive substance gives off energy which in turn is used to produce the images. PET can provide more helpful information than either CT or MRI scans. It is useful to see if the cancer has spread to the lymph nodes and it is also useful for your doctor to locate where the cancer has spread.
PET scan has been shown to be highly sensitive and specific, when combined with MRI it can achieve 100% diagnostic efficacy.[1][2] The use of PET scan has led to earlier diagnosis of multiple myeloma, more accurate therapy assessment, and better prediction of patient outcome. However, these have not been employed as a standard of care by the International Myeloma Working Group.[3]
References
- ↑ Shortt, CP.; Gleeson, TG.; Breen, KA.; McHugh, J.; O'Connell, MJ.; O'Gorman, PJ.; Eustace, SJ. (2009). "Whole-Body MRI versus PET in assessment of multiple myeloma disease activity". AJR Am J Roentgenol. 192 (4): 980–6. doi:10.2214/AJR.08.1633. PMID 19304704. Unknown parameter
|month=
ignored (help) - ↑ Agarwal, A.; Chirindel, A.; Shah, BA.; Subramaniam, RM. (2013). "Evolving role of FDG PET/CT in multiple myeloma imaging and management". AJR Am J Roentgenol. 200 (4): 884–90. doi:10.2214/AJR.12.9653. PMID 23521465. Unknown parameter
|month=
ignored (help) - ↑ Dimopoulos, M.; Terpos, E.; Comenzo, RL.; Tosi, P.; Beksac, M.; Sezer, O.; Siegel, D.; Lokhorst, H.; Kumar, S. (2009). "International myeloma working group consensus statement and guidelines regarding the current role of imaging techniques in the diagnosis and monitoring of multiple Myeloma". Leukemia. 23 (9): 1545–56. doi:10.1038/leu.2009.89. PMID 19421229. Unknown parameter
|month=
ignored (help)