Ramipril drug interactions: Difference between revisions

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<ref name="dailymed.nlm.nih.gov">{{Cite web  | last =  | first =  | title = ALTACE (RAMIPRIL) CAPSULE [PFIZER LABORATORIES DIV PFIZER INC] | url = http://dailymed.nlm.nih.gov/dailymed/lookup.cfm?setid=0fc34cd8-86e6-4034-73bd-4263a68ba046 | publisher =  | date =  | accessdate = }}</ref>
==References==
{{Reflist}}
{{FDA}}
[[Category:Cardiovascular Drugs]]
[[Category:Drugs]]


==Drug interactions==
==Drug interactions==

Revision as of 16:23, 18 February 2014


Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Ahmed Zaghw, M.D. [2], Amr Marawan, M.D. [3]

For patient information about Ramipril, click here.

Ramipril

Overview

Ramipril tablet is an angiontensin converting enzyme inhibitor drug that is FDA approved for the treatment of hypertension, heart failure, left ventricular dysfunction after myocardial infarction, diabetic nephropathy. Adverse reactions include hypotension, rash, hyperkalemia, disorder of taste, cough. hypotension, rash, hyperkalemia, disorder of taste, cough.

Category

Antihypertensive Agents, Angiotensin Converting Enzyme Inhibitors. Editor-In-Chief: C. Michael Gibson, M.S., M.D. [4]; Associate Editor(s)-in-Chief: Amr Marawan, M.D. [5]

[1]


References

  1. "ALTACE (RAMIPRIL) CAPSULE [PFIZER LABORATORIES DIV PFIZER INC]".

Adapted from the FDA Package Insert.


Drug interactions


Antacids

Capsaicin

Digoxin

Diuretics

Indomethacin, salicylates (e.g, aspirin)

Lithium

Loop diuretics

Phenothiazines

Potassium supplements, potassium-sparing diuretics

Laboratory Test Interactions




Antacids

Ramipril bioavailability may be decreased. Separate administration times by 1 to 2 h.

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Capsaicin

May exacerbate cough.

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Digoxin

Increased or decreased digoxin levels.

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Diuretics

Increased risk of hypotension.

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Indomethacin, salicylates (e.g, aspirin)

May reduce hypotensive effects, especially in low-renin or volume-dependent hypertensive patients.

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Lithium

May cause increased lithium levels and symptoms of lithium toxicity.

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Loop diuretics

Effects of loop diuretics may be decreased.

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Phenothiazines

Enhanced hypotensive effects.

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Potassium supplements, potassium-sparing diuretics

May cause increased potassium (serum) levels.

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Laboratory Test Interactions

False elevation of liver enzymes, serum bilirubin, uric acid, and blood glucose may occur.

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Complete list of drug interactions

Major Interactions

Moderate Interactions

Minor Interactions




Adapted from the FDA Package Insert.