Sandbox/pyelo

Acute Pyelonephritis, Outpatient Preferred Regimen ▸ Ciprofloxacin 500 mg PO q12h for 7 days WITH OR WITHOUT ▸ Ciprofloxacin 400 mg IV x 1 dose Alternative Regimen ▸ Ciprofloxacin 1000 mg PO q24h for 7 days OR ▸ Levofloxacin 750 mg PO q24h for 5 days OR ▸ TMP/SMZ 160/800 mg PO q12h for 14 days If FQ resistance >10%, add 1 IV dose of Ceftriaxone 1 g OR Gentamicin 5–7 mg/kg.

Acute Pyelonephritis, Inpatient Preferred Regimen ▸ Ciprofloxacin 400 mg IV q12h OR ▸ Levofloxacin 750 mg IV q24h OR ▸ Gentamicin 5–7 mg/kg IV q24h OR ▸ Ceftriaxone 1–2 gm IV q24h OR ▸ Cefotaxime 2 gm IV q8h OR ▸ Piperacillin/Tazobactam 3.375 gm IV q4–6h OR ▸ Ertapenem 1 gm IV q24h OR ▸ Doripenem 500 mg IV q8h The choice of antiobiotics should be based on resistance pattern.