Digoxin: Difference between revisions
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==Overview== | ==Overview== | ||
'''Digoxin''' [[International Nonproprietary Name|INN]]is a purified [[cardiac glycoside]] similar to [[Digitoxin]] extracted from the [[foxglove]] plant, ''[[Digitalis lanata]]'',<ref>{{cite journal | author = Hollman A | title = Digoxin comes from ''Digitalis lanata'' | journal = [[British Medical Journal]] | year = 1996 | volume = 312 | issue = 7035 | page = 912 | url = http://www.bmj.com/cgi/content/full/312/7035/912 }}</ref> which was discovered by [[William Withering]]. Its corresponding [[aglycone]] is [[digoxigenin]], and its [[acetyl]] derivative is [[acetyldigoxin]]. Digoxin is widely used in the treatment of various [[heart disease|heart conditions]], namely [[atrial fibrillation]], [[atrial flutter]] and sometimes [[heart failure]] that cannot be controlled by other [[medication]]. | '''Digoxin''' [[International Nonproprietary Name|INN]] is a purified [[cardiac glycoside]] similar to [[Digitoxin]] extracted from the [[foxglove]] plant, ''[[Digitalis lanata]]'',<ref>{{cite journal | author = Hollman A | title = Digoxin comes from ''Digitalis lanata'' | journal = [[British Medical Journal]] | year = 1996 | volume = 312 | issue = 7035 | page = 912 | url = http://www.bmj.com/cgi/content/full/312/7035/912 }}</ref> which was discovered by [[William Withering]]. Its corresponding [[aglycone]] is [[digoxigenin]], and its [[acetyl]] derivative is [[acetyldigoxin]]. Digoxin is widely used in the treatment of various [[heart disease|heart conditions]], namely [[atrial fibrillation]], [[atrial flutter]] and sometimes [[heart failure]] that cannot be controlled by other [[medication]]. | ||
==Category== | ==Category== | ||
Revision as of 21:07, 22 February 2014
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Ahmed Zaghw, M.D. [2]
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Overview
Digoxin INN is a purified cardiac glycoside similar to Digitoxin extracted from the foxglove plant, Digitalis lanata,[1] which was discovered by William Withering. Its corresponding aglycone is digoxigenin, and its acetyl derivative is acetyldigoxin. Digoxin is widely used in the treatment of various heart conditions, namely atrial fibrillation, atrial flutter and sometimes heart failure that cannot be controlled by other medication.
Category
US Brand Names
LANOXIN®, DIGOXIN®
FDA Package Insert
| Indications and Usage | Dosage and Administration | Dosage Forms and Strengths | Contraindications | Warnings and Precautions | Adverse Reactions | Drug Interactions | Use in Specific Populations | Overdosage | Description | Clinical Pharmacology | Nonclinical Toxicology | Clinical Studies | How Supplied/Storage and Handling | Patient Counseling Information | Labels and Packages
Mechanism of Action
References
- ↑ Hollman A (1996). "Digoxin comes from Digitalis lanata". British Medical Journal. 312 (7035): 912.