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==Overview==
==Overview==
An '''altered level of consciousness''' is any measure of arousal other than normal.  '''Level of consciousness''' ('''LOC''') is a measurement of a person's [[arousal|arousability]] and responsiveness to [[Stimulus (physiology)|stimuli]] from the environment.<ref name="Kandel00">
{{cite book |author=Kandel ER, Jessell, Thomas M.;  Schwartz, James H. |title=Principles of neural science |publisher=McGraw-Hill |location=New York |year=2000 |pages=901 |isbn=0-8385-7701-6 |oclc= |doi= |accessdate=2008-07-03 |url = http://books.google.com/?id=yzEFK7Xc87YC&pg=PA901&dq=%22level+of+consciousness%22}}</ref>  A mildly depressed level of [[consciousness]] or [[alertness]] may be classed as [[lethargy]]; someone in this state can be aroused with little difficulty.<ref name="Kandel00"/>  People who are [[Obtundation|obtunded]] have a more depressed level of consciousness and cannot be fully aroused.<ref name="Kandel00"/><ref name="Porth07"/>  Those who are not able to be aroused from a sleep-like state are said to be [[stupor]]ous.<ref name="Kandel00"/><ref name="Porth07"/>  [[Coma]] is the inability to make any purposeful response.<ref name="Kandel00"/><ref name="Porth07"/>  Scales such as the [[Glasgow coma scale]] have been designed to measure the level of consciousness.
An altered level of consciousness can result from a variety of factors, including alterations in the chemical environment of the brain (e.g. exposure to [[poison]]s or [[intoxicant]]s), insufficient [[oxygen]] or [[blood flow]] in the brain, and excessive [[intracranial pressure|pressure within the skull]].  <!--Level of consciousness may decline abruptly or slowly, or it may increase and decrease intermittently.<ref name="Dohert05"/>--> Prolonged unconsciousness is understood to be a sign of a [[medical emergency]].<ref name="Pollak02"/>  A deficit in the level of consciousness suggests that both of the [[cerebral hemisphere]]s or the [[reticular activating system]] have been injured.<ref name="Porth071">Porth, p. 838</ref>  A decreased level of consciousness correlates to increased morbidity ([[disability]]) and [[mortality rate|mortality]] (death).<ref name="Scheld041">Scheld ''et al.''. p. 530</ref> Thus it is a valuable measure of a patient's medical and neurological status.  In fact, some sources consider level of consciousness to be one of the [[vital sign]]s.<ref name="Pollak02"/><ref name="Forgey99">

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Pratik Bahekar, MBBS [2]


Overview

An altered level of consciousness is any measure of arousal other than normal. Level of consciousness (LOC) is a measurement of a person's arousability and responsiveness to stimuli from the environment.[1] A mildly depressed level of consciousness or alertness may be classed as lethargy; someone in this state can be aroused with little difficulty.[1] People who are obtunded have a more depressed level of consciousness and cannot be fully aroused.[1][2] Those who are not able to be aroused from a sleep-like state are said to be stuporous.[1][2] Coma is the inability to make any purposeful response.[1][2] Scales such as the Glasgow coma scale have been designed to measure the level of consciousness.

An altered level of consciousness can result from a variety of factors, including alterations in the chemical environment of the brain (e.g. exposure to poisons or intoxicants), insufficient oxygen or blood flow in the brain, and excessive pressure within the skull. Prolonged unconsciousness is understood to be a sign of a medical emergency.[3] A deficit in the level of consciousness suggests that both of the cerebral hemispheres or the reticular activating system have been injured.[4] A decreased level of consciousness correlates to increased morbidity (disability) and mortality (death).[5] Thus it is a valuable measure of a patient's medical and neurological status. In fact, some sources consider level of consciousness to be one of the vital signs.[3]<ref name="Forgey99">

  1. 1.0 1.1 1.2 1.3 1.4 Kandel ER, Jessell, Thomas M.; Schwartz, James H. (2000). Principles of neural science. New York: McGraw-Hill. p. 901. ISBN 0-8385-7701-6. Retrieved 2008-07-03.
  2. 2.0 2.1 2.2
  3. 3.0 3.1
  4. Porth, p. 838
  5. Scheld et al.. p. 530