Reteplase contraindications: Difference between revisions
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Because thrombolytic therapy increases the risk of bleeding, Retavase® is contraindicated in the following situations<ref name="dailymed.nlm.nih.gov">{{Cite web | last = | first = | title = RETAVASE (RETEPLASE) KIT [EKR THERAPEUTICS, INC.] | url =http://dailymed.nlm.nih.gov/dailymed/lookup.cfm?setid=e9ae6656-977c-4105-8528-bee664aab27a | publisher = | date = |accessdate = }}</ref>: | Because thrombolytic therapy increases the risk of bleeding, Retavase® is contraindicated in the following situations<ref name="dailymed.nlm.nih.gov">{{Cite web | last = | first = | title = RETAVASE (RETEPLASE) KIT [EKR THERAPEUTICS, INC.] | url =http://dailymed.nlm.nih.gov/dailymed/lookup.cfm?setid=e9ae6656-977c-4105-8528-bee664aab27a | publisher = | date = |accessdate = }}</ref>: | ||
'''*Active internal [[bleeding]] | |||
*History of [[cerebrovascular accident]] | |||
*Recent intracranial or intraspinal surgery or trauma (see [[Reteplase warnings|WARNINGS]]) | |||
*Intracranial neoplasm, [[arteriovenous malformation]], or [[aneurysm]] | |||
*Known bleeding [[diathesis]] | |||
*Severe uncontrolled [[hypertension]]'''<ref name="dailymed.nlm.nih.gov">{{Cite web | last = | first = | title = RETAVASE (RETEPLASE) KIT [EKR THERAPEUTICS, INC.] | url =http://dailymed.nlm.nih.gov/dailymed/lookup.cfm?setid=e9ae6656-977c-4105-8528-bee664aab27a | publisher = | date = |accessdate = }}</ref>: | |||
==References== | ==References== | ||
{{Reflist}} | {{Reflist}} | ||
{{FDA}} | {{FDA}} | ||
[[Category:Cardiovascular Drugs]] | |||
[[Category:Drugs]] | [[Category:Drugs]] |
Revision as of 05:26, 4 March 2014
Reteplase |
---|
Retavase® FDA Package Insert |
Indications and Usage |
Dosage and Administration |
Contraindications |
Warnings and Precautions |
Adverse Reactions |
Drug Interactions |
Use in Specific Populations |
Description |
Clinical Pharmacology |
Nonclinical Toxicology |
How Supplied/Storage and Handling |
Labels and Packages |
Clinical Trials on Reteplase |
ClinicalTrials.gov |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Ahmed Zaghw, M.D. [2]
Contraindications
Because thrombolytic therapy increases the risk of bleeding, Retavase® is contraindicated in the following situations[1]:
*Active internal bleeding
- History of cerebrovascular accident
- Recent intracranial or intraspinal surgery or trauma (see WARNINGS)
- Intracranial neoplasm, arteriovenous malformation, or aneurysm
- Known bleeding diathesis
- Severe uncontrolled hypertension[1]:
References
Adapted from the FDA Package Insert.