Mecamylamine: Difference between revisions

Mecamylamine
Clinical data
ATC code	C02BB01 (WHO) ;
Legal status
Legal status	In general: ℞ (Prescription only);
Pharmacokinetic data
Protein binding	40%
Identifiers
	IUPAC name N,2,3,3-tetramethylnorbornan-2-amine;
CAS Number	60-40-2 82924-03-6;
PubChem CID	4032;
DrugBank	APRD00458;
E number	{{#property:P628}}
ECHA InfoCard	{{#property:P2566}}Lua error in Module:EditAtWikidata at line 36: attempt to index field 'wikibase' (a nil value).
Chemical and physical data
Formula	C11H21N
Molar mass	167.291 g/mol

VisualWikitext

Revision as of 22:16, 7 March 2014

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Overview

Mecamylamine is a nicotinic antagonist that is well absorbed from the gastrointestinal tract and crosses the blood-brain barrier. Mecamylamine has been used as a ganglionic blocker in treating hypertension, but, like most ganglionic blockers, is more often used now as a research tool.

Mecamylamine is also sometimes used as an anti-addictive drug to help people stop smoking tobacco, and is now more widely used for this application than it is for lowering blood pressure. This effect is thought to be due to it blocking α3β4 nicotinic receptors in the brain.

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Template:WikiDoc Sources

v t e Antihypertensives (C02) and diuretics (C03)
Sympatholytic agents	Template:Navbox subgroup
Vasodilators	Diazoxide • hydrazinophthalazine (Hydralazine, Dihydralazine, Endralazine, Cadralazine) • Minoxidil • Nitroprusside • Phentolamine
Other antihypertensives	serotonin antagonist (Ketanserin) • endothelin receptor antagonist (Bosentan, Ambrisentan, Sitaxsentan) • MAOI (Pargyline) • THI (Metirosine)
Diuretics	Template:Navbox subgroup

Revision as of 17:14, 9 August 2012 (view source) WikiBot (talk \| contribs) m (Robot: Automated text replacement (-{{SIB}} + & -{{EH}} + & -{{EJ}} + & -{{Editor Help}} + & -{{Editor Join}} +)) ← Older edit	Revision as of 22:16, 7 March 2014 (view source) Gerald Chi (talk \| contribs) m (Changed protection level for "Mecamylamine" ([Edit=Allow only autoconfirmed users] (expires 22:16, 21 March 2014 (UTC)) [Move=Allow only autoconfirmed users] (expires 22:16, 21 March 2014 (UTC)))) Newer edit →
(No difference)

Clinical data

ATC code	C02BB01 (WHO)
Legal status
Legal status	In general: ℞ (Prescription only)
Pharmacokinetic data
Protein binding	40%
Identifiers
IUPAC name N,2,3,3-tetramethylnorbornan-2-amine
CAS Number	60-40-2 82924-03-6
PubChem CID	4032
DrugBank	APRD00458
E number	{{#property:P628}}
ECHA InfoCard	{{#property:P2566}}Lua error in Module:EditAtWikidata at line 36: attempt to index field 'wikibase' (a nil value).
Chemical and physical data
Formula	C₁₁H₂₁N
Molar mass	167.291 g/mol

Mecamylamine: Difference between revisions

Revision as of 22:16, 7 March 2014

Overview

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