Somnolence: Difference between revisions
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==Causes== | ==Causes== | ||
* Advanced sleep phase disorder | * [[Advanced sleep phase syndrome|Advanced sleep phase disorder]] | ||
* [[African trypanosomiasis]] ("sleeping sickness") | * [[African trypanosomiasis]] ("sleeping sickness") | ||
* [[Alice in Wonderland syndrome]] | * [[Alice in Wonderland syndrome]] | ||
* [[Cerebral edema| | * [[Cerebral edema|Brain edema]] | ||
* [[Cerebral hypoxia]] | * [[Cerebral hypoxia]] | ||
* [[Chronic fatigue syndrome]] | * [[Chronic fatigue syndrome]] | ||
* [[Clinical depression]], especially [[seasonal affective disorder]] | * [[Clinical depression]], especially [[seasonal affective disorder]] | ||
* [[Dehydration]] | * [[Dehydration]] | ||
* [[Delayed sleep phase syndrome]] | * [[Delayed sleep phase syndrome]] | ||
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* [[Increased intracranial pressure]]; for example, [[brain tumors]] | * [[Increased intracranial pressure]]; for example, [[brain tumors]] | ||
* [[Infectious mononucleosis]] (glandular fever) | * [[Infectious mononucleosis]] (glandular fever) | ||
* [[Intracranial hemorrhage]] such as due to | * [[Intracranial hemorrhage]] such as due to [[Aneurysm natural history, complications and prognosis#Complications|ruptured aneurysm]] | ||
* [[Lyme disease]] | * [[Lyme disease]] | ||
* [[Medications]] | * [[Medications]] | ||
** [[Analgesics]]: mostly prescribed or illicit [[opiates]] such as [[oxycontin]] or [[heroin]] | ** [[Analgesics]]: mostly prescribed or illicit [[opiates]] such as [[oxycontin]] or [[heroin]] | ||
Revision as of 18:35, 11 March 2014
For patient information, click here
| Somnolence | |
| ICD-10 | R40.0 |
|---|---|
| ICD-9 | 780.09 |
Template:Search infobox Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] ; Associate Editor(s)-in-Chief: Pratik Bahekar, MBBS [2]
Overview
Somnolence (or "drowsiness") is a state of near-sleep, a strong desire for sleep, or sleeping for unusually long periods. It has two distinct meanings, referring both to the usual state preceding falling asleep, and the chronic condition referring to being in that state independent of a circadian rhythm. The disorder characterized by the latter condition is most commonly associated with users of prescription hypnotics, such as mirtazapine or zolpidem.
It is considered a lesser impairment of consciousness than stupor or coma.
Causes
- Advanced sleep phase disorder
- African trypanosomiasis ("sleeping sickness")
- Alice in Wonderland syndrome
- Brain edema
- Cerebral hypoxia
- Chronic fatigue syndrome
- Clinical depression, especially seasonal affective disorder
- Dehydration
- Delayed sleep phase syndrome
- Diabetic ketoacidosis as example, but not balanced diabetes mellitus
- Encephalitis – (viral, bacterial or other agents)
- Epilepsy – after seizure
- Fibromyalgia
- Hydrocephalus
- Hyperparathyroidism
- Hypothermia
- Hypothyroidism
- Increased intracranial pressure; for example, brain tumors
- Infectious mononucleosis (glandular fever)
- Intracranial hemorrhage such as due to ruptured aneurysm
- Lyme disease
- Medications
- Analgesics: mostly prescribed or illicit opiates such as oxycontin or heroin
- Antiepileptics such as phenytoin, carbamazepine, gabapentin
- Antidepressants: for instance sedating tricyclic antidepressants[1] and mirtazapine. Somnolence is less common with SSRI[2] and SNRI as well as MAOI.
- Antihistamines: diphenhydramine and doxylamine
- Antipsychotics: thioridazine, quetiapine, olanzapine, risperidone, and ziprasidone but not haloperidol
- Dopamine agonists used in the treatment of parkinson's disease e.g. pergolide, ropinirole and pramipexole.
- HIV medications for example, efavirenz
- Antihypertensive medications like amlodipine
- Hypnotics like zopiclone, or the benzodiazepine such as diazepam or nitrazepam and the barbiturate, such as amobarbital or secobarbital
- Other agents impacting the central nervous system in sufficient or toxic doses
- Starvation
- Sleep apnea
- Stroke
- Traumatic brain injury
- Treatment of primary insomina may cause somnolence:
- Flurazepam
- Benzodiazepine
- Quazepam
- Estazolam
- Temazepam
- Triazolam
- Benzodiazepine receptor agonists: Eszopiclone, Zolpidem, Zaleplon
- Melatonin receptor agonists: Ramelteon[3]
Hazards
Somnolence can be dangerous when performing tasks that require constant concentration, such as driving a vehicle. When a person is sufficiently fatigued, he or she may experience microsleeps (loss of concentration).
See also
- Sleep Disorders
- Chronic fatigue syndrome
- Fibromyalgia
- Insomnia
- Hypersomnia
- Dyssomnia
- Fatigue (physical)
- Restless legs syndrome
References
- ↑ Zimmermann C, Pfeiffer H (January 2007). "[Sleep disorders in depression. Suggestions for a therapeutic approach]". Nervenarzt (in German). 78 (1): 21–30. doi:10.1007/s00115-006-2111-1. PMID 16832696.
- ↑ Watanabe N, Omori IM, Nakagawa A; et al. (2011). "Mirtazapine versus other antidepressive agents for depression". Cochrane Database Syst Rev (12): CD006528. doi:10.1002/14651858.CD006528.pub2. PMID 22161405.
- ↑ "http://www.dsm5.org/Pages/Default.aspx". External link in
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Template:Cognition, perception, emotional state and behaviour symptoms and signs Template:SleepSeries2