Peptic ulcer differential diagnosis: Difference between revisions
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==Differentiating Peptic Ulcer from other Diseases== | ==Differentiating Peptic Ulcer from other Diseases== | ||
*[[Acute upper gastrointestinal bleeding]] | *[[Acute upper gastrointestinal bleeding]]: PUD accounts for the majority of acute episodes of gastrointestinal bleeding<ref name="pmid18753649">{{cite journal| author=Gralnek IM, Barkun AN, Bardou M| title=Management of acute bleeding from a peptic ulcer. | journal=N Engl J Med | year= 2008 | volume= 359 | issue= 9 | pages= 928-37 | pmid=18753649 | doi=10.1056/NEJMra0706113 | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=18753649 }} </ref> (up to 40%)<ref name="pmid11701581">{{cite journal| author=Dallal HJ, Palmer KR| title=ABC of the upper gastrointestinal tract: Upper gastrointestinal haemorrhage. | journal=BMJ | year= 2001 | volume= 323 | issue= 7321 | pages= 1115-7 | pmid=11701581 | doi= | pmc=PMC1121602 | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=11701581 }} </ref>, but there are other causes:<ref name="pmid22534226">{{cite journal| author=Wilkins T, Khan N, Nabh A, Schade RR| title=Diagnosis and management of upper gastrointestinal bleeding. | journal=Am Fam Physician | year= 2012 | volume= 85 | issue= 5 | pages= 469-76 | pmid=22534226 | doi= | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=22534226 }} </ref> | ||
**Esophageal varices: history of cirrhosis (and portal hypertension) | |||
**Mallory-Weiss syndrome: history of repeated vomiting | |||
**Gastrointestinal cancer: history of anorexia or weight loss, tobacco smoking, alcohol drinking. | |||
**Arteriovenous malformations: Painless bleeding in patients >70 year, history of iron deficiency anemia. | |||
**Esophagitis or esophageal ulcer: heartburn, indigestion, or dysphagia | |||
**Dieulafoy ulcer: painless bleeding | |||
*[[Alpha-1 Antitrypsin Deficiency]] | *[[Alpha-1 Antitrypsin Deficiency]] | ||
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Peptic ulcer Microchapters |
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Treatment |
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Surgery |
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Case Studies |
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2017 ACG Guidelines for Peptic Ulcer Disease |
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Guidelines for the Indications to Test for, and to Treat, H. pylori Infection |
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Guidlines for factors that predict the successful eradication when treating H. pylori infection |
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Guidelines to document H. pylori antimicrobial resistance in the North America |
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Guidelines for evaluation and testing of H. pylori antibiotic resistance |
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Guidelines for when to test for treatment success after H. pylori eradication therapy |
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Guidelines for penicillin allergy in patients with H. pylori infection |
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Peptic ulcer differential diagnosis On the Web |
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Risk calculators and risk factors for Peptic ulcer differential diagnosis |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Differentiating Peptic Ulcer from other Diseases
- Acute upper gastrointestinal bleeding: PUD accounts for the majority of acute episodes of gastrointestinal bleeding[1] (up to 40%)[2], but there are other causes:[3]
- Esophageal varices: history of cirrhosis (and portal hypertension)
- Mallory-Weiss syndrome: history of repeated vomiting
- Gastrointestinal cancer: history of anorexia or weight loss, tobacco smoking, alcohol drinking.
- Arteriovenous malformations: Painless bleeding in patients >70 year, history of iron deficiency anemia.
- Esophagitis or esophageal ulcer: heartburn, indigestion, or dysphagia
- Dieulafoy ulcer: painless bleeding
- Alpha-1 Antitrypsin Deficiency
- Basophilic leukemia
- Chronic debilitated conditions
- Chronic obstructive pulmonary disease
- Chronic Renal Failure
- Cirrhosis
- Cystic Fibrosis
- Glucosteroids
- Gastroesophageal reflux disease (GERD)
- Hyperparathyroidism
- Incompetant gastroesophageal sphincter
- Severe systemic disease
- Zollinger-Ellison Syndrome
References
- ↑ Gralnek IM, Barkun AN, Bardou M (2008). "Management of acute bleeding from a peptic ulcer". N Engl J Med. 359 (9): 928–37. doi:10.1056/NEJMra0706113. PMID 18753649.
- ↑ Dallal HJ, Palmer KR (2001). "ABC of the upper gastrointestinal tract: Upper gastrointestinal haemorrhage". BMJ. 323 (7321): 1115–7. PMC 1121602. PMID 11701581.
- ↑ Wilkins T, Khan N, Nabh A, Schade RR (2012). "Diagnosis and management of upper gastrointestinal bleeding". Am Fam Physician. 85 (5): 469–76. PMID 22534226.