Peptic ulcer differential diagnosis: Difference between revisions
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**Esophagitis or esophageal ulcer: heartburn, indigestion, or dysphagia | **Esophagitis or esophageal ulcer: heartburn, indigestion, or dysphagia | ||
**Dieulafoy ulcer: painless bleeding | **Dieulafoy ulcer: painless bleeding | ||
*[[Alpha-1 Antitrypsin Deficiency]] | *[[Alpha-1 Antitrypsin Deficiency]] [[AATD]]: besides lung disease, liver disease (hepatitis, cirrhosis, and hepatoma) represents another clinical manifestation of AATD,<ref name="pmid21960536 [">{{cite journal| author=Stoller JK, Aboussouan LS| title=A review of α1-antitrypsin deficiency. | journal=Am J Respir Crit Care Med | year= 2012 | volume= 185 | issue= 3 | pages= 246-59 | pmid=21960536 [ | doi=10.1164/rccm.201108-1428CI | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=21960536 }} </ref><ref name="pmid19553648">{{cite journal| author=Silverman EK, Sandhaus RA| title=Clinical practice. Alpha1-antitrypsin deficiency. | journal=N Engl J Med | year= 2009 | volume= 360 | issue= 26 | pages= 2749-57 | pmid=19553648 | doi=10.1056/NEJMcp0900449 | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=19553648 }} </ref> therefore those patients can present upper gastrointestinal bleeding and abdominal pain, in the context of altered liver function.<ref name="pmid22200689">{{cite journal| author=Nelson DR, Teckman J, Di Bisceglie AM, Brenner DA| title=Diagnosis and management of patients with α1-antitrypsin (A1AT) deficiency. | journal=Clin Gastroenterol Hepatol | year= 2012 | volume= 10 | issue= 6 | pages= 575-80 | pmid=22200689 | doi=10.1016/j.cgh.2011.12.028 | pmc=PMC3360829 | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=22200689 }} </ref> | ||
*Basophilic leukemia | *Basophilic leukemia | ||
*Chronic debilitated conditions | *Chronic debilitated conditions | ||
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Peptic ulcer Microchapters |
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Treatment |
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Surgery |
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Case Studies |
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2017 ACG Guidelines for Peptic Ulcer Disease |
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Guidelines for the Indications to Test for, and to Treat, H. pylori Infection |
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Guidlines for factors that predict the successful eradication when treating H. pylori infection |
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Guidelines to document H. pylori antimicrobial resistance in the North America |
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Guidelines for evaluation and testing of H. pylori antibiotic resistance |
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Guidelines for when to test for treatment success after H. pylori eradication therapy |
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Guidelines for penicillin allergy in patients with H. pylori infection |
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Peptic ulcer differential diagnosis On the Web |
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American Roentgen Ray Society Images of Peptic ulcer differential diagnosis |
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Risk calculators and risk factors for Peptic ulcer differential diagnosis |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Differentiating Peptic Ulcer from other Diseases
- Acute upper gastrointestinal bleeding: PUD accounts for the majority of acute episodes of gastrointestinal bleeding[1] (up to 40%)[2], but there are other causes:[3]
- Esophageal varices: history of cirrhosis (and portal hypertension)
- Mallory-Weiss syndrome: history of repeated vomiting
- Gastrointestinal cancer: history of anorexia or weight loss, tobacco smoking and alcohol drinking.
- Arteriovenous malformations: Painless bleeding in >70 years old patients, history of iron deficiency anemia.
- Esophagitis or esophageal ulcer: heartburn, indigestion, or dysphagia
- Dieulafoy ulcer: painless bleeding
- Alpha-1 Antitrypsin Deficiency AATD: besides lung disease, liver disease (hepatitis, cirrhosis, and hepatoma) represents another clinical manifestation of AATD,[4][5] therefore those patients can present upper gastrointestinal bleeding and abdominal pain, in the context of altered liver function.[6]
- Basophilic leukemia
- Chronic debilitated conditions
- Chronic obstructive pulmonary disease
- Chronic Renal Failure
- Cirrhosis
- Cystic Fibrosis
- Glucosteroids
- Gastroesophageal reflux disease (GERD)
- Hyperparathyroidism
- Incompetant gastroesophageal sphincter
- Severe systemic disease
- Zollinger-Ellison Syndrome
References
- ↑ Gralnek IM, Barkun AN, Bardou M (2008). "Management of acute bleeding from a peptic ulcer". N Engl J Med. 359 (9): 928–37. doi:10.1056/NEJMra0706113. PMID 18753649.
- ↑ Dallal HJ, Palmer KR (2001). "ABC of the upper gastrointestinal tract: Upper gastrointestinal haemorrhage". BMJ. 323 (7321): 1115–7. PMC 1121602. PMID 11701581.
- ↑ Wilkins T, Khan N, Nabh A, Schade RR (2012). "Diagnosis and management of upper gastrointestinal bleeding". Am Fam Physician. 85 (5): 469–76. PMID 22534226.
- ↑ Stoller JK, Aboussouan LS (2012). "A review of α1-antitrypsin deficiency". Am J Respir Crit Care Med. 185 (3): 246–59. doi:10.1164/rccm.201108-1428CI. PMID [ 21960536 [ Check
|pmid=value (help). - ↑ Silverman EK, Sandhaus RA (2009). "Clinical practice. Alpha1-antitrypsin deficiency". N Engl J Med. 360 (26): 2749–57. doi:10.1056/NEJMcp0900449. PMID 19553648.
- ↑ Nelson DR, Teckman J, Di Bisceglie AM, Brenner DA (2012). "Diagnosis and management of patients with α1-antitrypsin (A1AT) deficiency". Clin Gastroenterol Hepatol. 10 (6): 575–80. doi:10.1016/j.cgh.2011.12.028. PMC 3360829. PMID 22200689.