Peptic ulcer primary prevention

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Guidelines for the Indications to Test for, and to Treat, H. pylori Infection
Guidelines for First line Treatment Strategies of Peptic Ulcer Disease for Providers in North America
Guidlines for factors that predict the successful eradication when treating H. pylori infection
Guidelines to document H. pylori antimicrobial resistance in the North America
Guidelines for evaluation and testing of H. pylori antibiotic resistance
Guidelines for when to test for treatment success after H. pylori eradication therapy
Guidelines for penicillin allergy in patients with H. pylori infection
Guidelines for the salvage therapy
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Primary Prevention

Lifestyle changes may help prevent peptic ulcers:

Tips include:

• Avoid aspirin, ibuprofen, naproxen, and other NSAIDs. Try acetaminophen instead. If you must take such medicines, talk to your doctor first.
• Don't smoke or chew tobacco.
• Limit alcohol to no more than two drinks per day.

Patients on long-term NSAID therapy and with the following risk factors, present an elevated risk of gastrointestinal bleeding and perforation:

• History of ulcer complication.
• History of ulcer disease (non-bleeding).
• Dual antiplatelet therapy.
• Concomitant anticoagulant therapy
• ≥60 years
• Corticosteroid use
• Dyspepsia
• GERD symptoms.
• Helicobacter pylori infection: there is a potential advantage of eradicating the infection