Sandbox/Alejandro: Difference between revisions
< Sandbox
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| style="padding: 0 5px; font-size: 90%; background: #F5F5F5;" align=center | '''''Alternative Regimen 1 ''''' | | style="padding: 0 5px; font-size: 90%; background: #F5F5F5;" align=center | '''''Alternative Regimen 1 ''''' | ||
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| style="font-size: 90%; padding: 0 5px; background: #DCDCDC;" align=left | ▸ '''''[[Amikacin]] 15 mg/kg/day IV/IM divided q8-12h (max: 15 mg/kg/day)'''''<br> OR <br> ▸ '''''[[Gentamicin]] 3-5 mg/kg/day IV/IM divided q6-8h'''''<br> OR <br> ▸ '''''[[Gentamicin]] 4-7 mg/kg/day IV | | style="font-size: 90%; padding: 0 5px; background: #DCDCDC;" align=left | ▸ '''''[[Amikacin]] 15 mg/kg/day IV/IM divided q8-12h (max: 15 mg/kg/day)'''''<br> OR <br> ▸ '''''[[Gentamicin]] 3-5 mg/kg/day IV/IM divided q6-8h'''''<br> OR <br> ▸ '''''[[Gentamicin]] 4-7 mg/kg/day IV q24h <small>(adjust dosage based on serum concentrations)</small>''''' | ||
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| style="font-size: 90%; padding: 0 5px; background: #DCDCDC;" align=left |PLUS | | style="font-size: 90%; padding: 0 5px; background: #DCDCDC;" align=left |PLUS |
Revision as of 16:14, 5 June 2014
Neutropenic Patients
- Patients with neutropenia require an antimicrobial therapy with a broader coverage.
- The duration of antimicrobial therapy should be individualized in accordance with patient's clinical response.
Microorganism | Duration of Therapy |
▸ Gram-negative Bacteria | 7-14 days |
▸ Gram-positive Bacteria | 7-10 days |
▸ Fungi | Until clinical resolution |
▸ Click on the following categories to expand treatment regimens.
Neutropenia ▸ Gram-Negative Bacteria ▸ Gram-Positive Bacteria ▸ Fungi
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Cellular Immune Deficient Patients
- Patients with cellular immunodeficiency require a pathogen-specific antimicrobial therapy.
- The duration of antimicrobial therapy should be individualized in accordance with patient's clinical response.
Microorganism | Duration of Therapy |
▸ Nocardia spp | 3-12 months |
▸ Atypical mycobacteria | 3-6 weeks |
▸ Cryptococcus spp | 8-12 weeks |
▸ Histoplasma spp | xxx |
▸ Varicella-zoster virus | 7-10 days |
▸ Herpes simplex virus | 7 days |
▸ Cytomegalovirus | 21 days |
Bacteria ▸ Nocardia spp ▸ Atypical mycobacteria Fungi ▸ Cryptococcus spp ▸ Histoplasma spp Viruses ▸ Varicella-zoster virus ▸ Herpes simplex virus ▸ Cytomegalovirus |
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- ↑ Wheat, LJ.; Freifeld, AG.; Kleiman, MB.; Baddley, JW.; McKinsey, DS.; Loyd, JE.; Kauffman, CA. (2007). "Clinical practice guidelines for the management of patients with histoplasmosis: 2007 update by the Infectious Diseases Society of America". Clin Infect Dis. 45 (7): 807–25. doi:10.1086/521259. PMID 17806045. Unknown parameter
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