Chikungunya medical therapy: Difference between revisions

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==Medical Therapy==
==Medical Therapy==
There is no specific treatment for Chikungunya. [[Vaccine]] trials were carried out in 2000, but funding for the project was discontinued  and there is no vaccine currently available. A [[serology|serological]] test for Chikungunya is available from the University of Malaya in Kuala Lumpur, Malaysia.


[[Chloroquine]] is gaining ground as a possible treatment for the symptoms associated with Chikungunya and as an antiviral agent to combat the Chikungunya virus. According to the University of Malaya, "In unresolved [[arthritis]] refractory to [[aspirin]] and nonsteroidal anti-inflammatory drugs, [[chloroquine]] phosphate (250 mg/day) has given promising results." [http://www.vadscorner.com/alphaviruses.html] Research by Italian scientist, Andrea Savarino, and his colleagues in addition a French government press release in March 2006 have added more credence to the claim that [[chloroquine]] may be effective in treating Chikungunya. The CDC fact sheet on Chikungunya advises against using Aspirin. Ibuprofen, Naproxen and other non-steroidal anti-inflammatory drugs are recommended for arthritic pain and fever.
* There is no specific antiviral therapy. The treatment is symptomatic:
 
** Assess hydration and hemodynamic status and provide supportive care as needed
Infected persons should limit further exposure to mosquito bites, stay indoors and under a mosquito net. Further, "supportive care with rest is preferred during the acute [[joint]] symptoms. Movement and mild exercise tend to improve stiffness and morning [[arthralgia]], but heavy exercise may exacerbate [[rheumatism|rheumatic]] symptoms." [http://www.vadscorner.com/alphaviruses.html]
** Evaluate for other serious conditions (e.g., dengue, malaria, and bacterial infections) and treat or manage appropriately
Arthralgia remains troublesome even after 8 months.
** Collect specimens for diagnostic testing
In Andhra Pradesh patients use donkey milk as medicine.In Kerala patients have relief by honey/lime mix.Some people get relief by having turmeric in low volume.
** Use acetaminophen or paracetamol for initial fever and pain control
Homoeopathy claims to have successful treatment for chikungunya. As they treat on symptomatology and not the diagnosis, they claim to have many medicines successful for prevention and cure of chikungunya.
** If inadequate, consider using narcotics or NSAIDs
**If the patient may have dengue, do not use aspirin or other NSAIDs (e.g., ibuprofen, naproxen, toradol) until they have been afebrile ≥48 hours and have no warning signs for severe dengue*
**Persistent joint pain may benefit from use of NSAIDs, corticosteroids, or physiotherapy


==References==
==References==

Revision as of 19:17, 5 June 2014

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Medical Therapy

  • There is no specific antiviral therapy. The treatment is symptomatic:
    • Assess hydration and hemodynamic status and provide supportive care as needed
    • Evaluate for other serious conditions (e.g., dengue, malaria, and bacterial infections) and treat or manage appropriately
    • Collect specimens for diagnostic testing
    • Use acetaminophen or paracetamol for initial fever and pain control
    • If inadequate, consider using narcotics or NSAIDs
    • If the patient may have dengue, do not use aspirin or other NSAIDs (e.g., ibuprofen, naproxen, toradol) until they have been afebrile ≥48 hours and have no warning signs for severe dengue*
    • Persistent joint pain may benefit from use of NSAIDs, corticosteroids, or physiotherapy

References

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