Dengue fever causes: Difference between revisions
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Dengue fever is caused by one of four different but related [[Dengue fever viruses]]. [[Aedes aegypti]] is the principal [[mosquito]] vector of [[dengue fever viruses]]. | Dengue fever is caused by one of four different but related [[Dengue fever viruses]]. [[Aedes aegypti]] is the principal [[mosquito]] vector of [[dengue fever viruses]]. | ||
==Dengue Fever Virus | ==Dengue Fever Virus== | ||
[[Dengue fever virus]] ([[DENV]]) is an [[RNA]] virus of the family [[Flaviviridae]]; genus [[Flavivirus]]. Other members of the same genus include [[yellow fever]] virus, [[West Nile virus]], [[St. Louis encephalitis]] virus, [[japanese encephalitis]] virus, [[tick-borne encephalitis]], [[Kyasanur Forest disease]] virus, and [[Omsk hemorrhagic fever virus]]. Most are transmitted by arthropods ([[mosquitoes]] or [[ticks]]), and are therefore also referred to as [[arboviruses]] (arthropod-borne viruses). | [[Dengue fever virus]] ([[DENV]]) is an [[RNA]] virus of the family [[Flaviviridae]]; genus [[Flavivirus]]. Other members of the same genus include [[yellow fever]] virus, [[West Nile virus]], [[St. Louis encephalitis]] virus, [[japanese encephalitis]] virus, [[tick-borne encephalitis]], [[Kyasanur Forest disease]] virus, and [[Omsk hemorrhagic fever virus]]. Most are transmitted by arthropods ([[mosquitoes]] or [[ticks]]), and are therefore also referred to as [[arboviruses]] (arthropod-borne viruses). | ||
Revision as of 19:06, 8 June 2014
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Overview
Dengue fever is caused by one of four different but related Dengue fever viruses. Aedes aegypti is the principal mosquito vector of dengue fever viruses.
Dengue Fever Virus
Dengue fever virus (DENV) is an RNA virus of the family Flaviviridae; genus Flavivirus. Other members of the same genus include yellow fever virus, West Nile virus, St. Louis encephalitis virus, japanese encephalitis virus, tick-borne encephalitis, Kyasanur Forest disease virus, and Omsk hemorrhagic fever virus. Most are transmitted by arthropods (mosquitoes or ticks), and are therefore also referred to as arboviruses (arthropod-borne viruses).
The dengue virus genome contains about 11,000 nucleotide bases, which code for the three different types of protein molecules (C, prM and E) that form the virus particle and seven other types of protein molecules (NS1, NS2a, NS2b, NS3, NS4a, NS4b, NS5) that are only found in infected host cells and are required for replication of the virus. There are five strains of the virus, of which the first four are referred to as DENV-1, DENV-2, DENV-3 and DENV-4. The distinctions between the serotypes is based on the their antigenicity.