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<nowiki>Insert non-formatted text here</nowiki>


 
{| style="font-size: 85%;"
{| style="border: 0px; font-size: 90%; margin: 3px;" align=center
! style="width: 80px; background: #4479BA; text-align: center;"|{{fontcolor|#FFF|Severity}}
! style="width: 300px;background: #4479BA"|{{fontcolor|#FFF| '''''Community-onset infection '''''}}
! style="width: 720px; background: #4479BA; text-align: center;"| {{fontcolor|#FFF|Criteria}}
! style="width: 300px;background: #4479BA"|{{fontcolor|#FFF| '''''Hospital-onset infection '''''}}
|-
| style="background: #F5F5F5; padding: 5px; text-align: center;"| '''Mild'''
| style="background: #DCDCDC; padding: 5px;"| Diarrhea as the only symptom
|-
| style="background: #F5F5F5; padding: 5px; text-align: center;"| '''Moderate'''
| style="background: #DCDCDC; padding: 5px;"| Raised white cell count but <15,000 cells/mL and serum creatine <nowiki><1.5 times baseline</nowiki>
|-
|-
| style="width: 120px;background: #F5F5F5"| Includes patients with 1 or more of the following conditions:
| style="background: #F5F5F5; padding: 5px; text-align: center;"| '''Severe:'''
*The presence of an invasive device at time of admission
| style="background: #DCDCDC; padding: 5px;"| Leucocytosis <nowiki>>15,000 cells/mL OR serum creatinene level >1.5</nowiki> times baseline or  abdominal tenderness and serum albumin < 3 g/dL
*History of [[MRSA]] infection or colonization
*History of surgery, hospitalization, [[dialysis]], or residence in a long-term care facility in the previous 12 months.
| style="width: 120px;background: #F5F5F5"| Includes patients with positive culture results obtained >48 h after admission. <br> Patients might also have 1 of the conditions described in community-onset infection.
|-
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| style="background: #F5F5F5; padding: 5px; text-align: center;"| '''Severe complicated'''
| style="background: #DCDCDC; padding: 5px;"| [[Hypotension]] or [[shock]], [[ileus]], [[megacolon]], [[leucocytosis]] >20,000 cells/mL OR [[leucopenia]] <nowiki><2,000, lactate ></nowiki>2.2 mmol/L, [[delirium]], [[fever]] ≥ 38.5 °C, organ failure
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Revision as of 19:44, 16 June 2014

The following table contains the main risk factors for CDI:[1][2][3][2][2]

Severity of the disease
Mild: diarrhea as the only symptom
Moderate: raised white cell count but <15,000 cells/mL and serum creatine <1.5 times baseline
Severe: leucocytosis >15,000 cells/mL OR serum creatinene level >1.5 times baseline or abdominal tenderness and serum albumin < 3 g/dL
Severe complicated: hypotension or shock, ileus, megacolon, leucocytosis >20,000 cells/mL OR leucopenia <2,000, lactate >2.2 mmol/L, delirium, fever ≥ 38.5 °C, organ failure

Insert non-formatted text here

Severity Criteria
Mild Diarrhea as the only symptom
Moderate Raised white cell count but <15,000 cells/mL and serum creatine <1.5 times baseline
Severe: Leucocytosis >15,000 cells/mL OR serum creatinene level >1.5 times baseline or abdominal tenderness and serum albumin < 3 g/dL
Severe complicated Hypotension or shock, ileus, megacolon, leucocytosis >20,000 cells/mL OR leucopenia <2,000, lactate >2.2 mmol/L, delirium, fever ≥ 38.5 °C, organ failure
  1. Hensgens MP, Goorhuis A, Dekkers OM, Kuijper EJ (2012). "Time interval of increased risk for Clostridium difficile infection after exposure to antibiotics". J Antimicrob Chemother. 67 (3): 742–8. doi:10.1093/jac/dkr508. PMID 22146873.
  2. 2.0 2.1 2.2 Knight, Christopher L.; Surawicz, Christina M. (2013). "Clostridium difficile Infection". Medical Clinics of North America. 97 (4): 523–536. doi:10.1016/j.mcna.2013.02.003. ISSN 0025-7125.
  3. Planche, Tim (2013). "Clostridium difficile". Medicine. 41 (11): 654–657. doi:10.1016/j.mpmed.2013.08.003. ISSN 1357-3039.