Measles medical therapy: Difference between revisions
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==Overview== | ==Overview== | ||
Despite the efforts made in the past years to develop a treatment regimen for [[measles]], there is still no specific [[Antiviral Therapy|antiviral therapy]] for uncomplicated cases of [[measles]], however, some [[drugs]] such as [[ribavirin]] and [[interferon-α]] have been used in the more severe cases of the condition, notably for cases of [[infection]] of the [[CNS]] by the [[virus]].<ref name="MossGriffin2012">{{cite journal|last1=Moss|first1=William J|last2=Griffin|first2=Diane E|title=Measles|journal=The Lancet|volume=379|issue=9811|year=2012|pages=153–164|issn=01406736|doi=10.1016/S0140-6736(10)62352-5}}</ref> | Despite the efforts made in the past years to develop a treatment regimen for [[measles]], there is still no specific [[Antiviral Therapy|antiviral therapy]] for uncomplicated cases of [[measles]], however, some [[drugs]] such as [[ribavirin]] and [[interferon-α]] have been used in the more severe cases of the condition, notably for cases of [[infection]] of the [[CNS]] by the [[virus]]. Yet, there is evidence that the administration of two doses of [[vitamin A]] in children, under the age of two, was associated with a reduced risk of [[morbidity]] and [[mortality]] from the disease. For most patients with the disease, the standard treatment is focused on supportive care.<ref name="MossGriffin2012">{{cite journal|last1=Moss|first1=William J|last2=Griffin|first2=Diane E|title=Measles|journal=The Lancet|volume=379|issue=9811|year=2012|pages=153–164|issn=01406736|doi=10.1016/S0140-6736(10)62352-5}}</ref><ref name="pmid16235283">{{cite journal| author=Huiming Y, Chaomin W, Meng M| title=Vitamin A for treating measles in children. | journal=Cochrane Database Syst Rev | year= 2005 | volume= | issue= 4 | pages= CD001479 | pmid=16235283 | doi=10.1002/14651858.CD001479.pub3 | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=16235283 }} </ref><ref name="pmid20390298">{{cite journal| author=Reuter D, Schneider-Schaulies J| title=Measles virus infection of the CNS: human disease, animal models, and approaches to therapy. | journal=Med Microbiol Immunol | year= 2010 | volume= 199 | issue= 3 | pages= 261-71 | pmid=20390298 | doi=10.1007/s00430-010-0153-2 | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=20390298 }} </ref> | ||
==Medical Therapy== | ==Medical Therapy== | ||
Revision as of 15:14, 24 June 2014
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: João André Alves Silva, M.D. [2]
Overview
Despite the efforts made in the past years to develop a treatment regimen for measles, there is still no specific antiviral therapy for uncomplicated cases of measles, however, some drugs such as ribavirin and interferon-α have been used in the more severe cases of the condition, notably for cases of infection of the CNS by the virus. Yet, there is evidence that the administration of two doses of vitamin A in children, under the age of two, was associated with a reduced risk of morbidity and mortality from the disease. For most patients with the disease, the standard treatment is focused on supportive care.[1][2][3]
Medical Therapy
References
- ↑ Moss, William J; Griffin, Diane E (2012). "Measles". The Lancet. 379 (9811): 153–164. doi:10.1016/S0140-6736(10)62352-5. ISSN 0140-6736.
- ↑ Huiming Y, Chaomin W, Meng M (2005). "Vitamin A for treating measles in children". Cochrane Database Syst Rev (4): CD001479. doi:10.1002/14651858.CD001479.pub3. PMID 16235283.
- ↑ Reuter D, Schneider-Schaulies J (2010). "Measles virus infection of the CNS: human disease, animal models, and approaches to therapy". Med Microbiol Immunol. 199 (3): 261–71. doi:10.1007/s00430-010-0153-2. PMID 20390298.