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* The damage to [[periphereal nerves]] was the first theory that attempted to explain the [[pathogenesis]] of vitiligo.<ref name="pmid13641799">{{cite journal| author=LERNER AB| title=Vitiligo. | journal=J Invest Dermatol | year= 1959 | volume= 32 | issue= 2, Part 2 | pages= 285-310 | pmid=13641799 | doi= | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=13641799 }} </ref> | * The damage to [[periphereal nerves]] was the first theory that attempted to explain the [[pathogenesis]] of vitiligo.<ref name="pmid13641799">{{cite journal| author=LERNER AB| title=Vitiligo. | journal=J Invest Dermatol | year= 1959 | volume= 32 | issue= 2, Part 2 | pages= 285-310 | pmid=13641799 | doi= | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=13641799 }} </ref> | ||
* Also, the relation between autoimmune diseases and vitiligo was observed. | * Also, the relation between autoimmune diseases and vitiligo was observed. | ||
==Impact on Cultural History== | |||
==References== | ==References== | ||
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Overview
Historical Perspective
- Descriptions of human pigmentation diseases have been made since thousands years.
- The first descriptions of what seems to be vitiligo were written approximately 3000 years ago in the Egyptian text Eber Papyrus[1] and in the Indian Vedic text Atharva Veda.[2]
- The Indian text, the Charak Samhita (800 B.C), describes “spreading whiteness” using the Sanskrit word “svitra”.
- The bible mentions a variety of skin diseases, such as leprosy, psoriasis and vitiligo, using one word: “Zara’at", which means "white spots".[3]
- Celsus was the first to use the word "vitiligo" in his book De Medicina (100 A.C.).
- The word "vitiligo" may have been derived from:[4][5]
- Vituli: white glistening of the flesh of calves
- Vitelius: calf
- VItum: blemish
- Vitulum: small blemish
- Moriz Kaposi was on of the first to describe the histopathology of vitiligo as a "lack of pigmented granules" in the skin.[5]
- The damage to periphereal nerves was the first theory that attempted to explain the pathogenesis of vitiligo.[6]
- Also, the relation between autoimmune diseases and vitiligo was observed.
Impact on Cultural History
References
- ↑ Nair BK (1978). "Vitiligo--a retrospect". Int J Dermatol. 17 (9): 755–7. PMID 365814.
- ↑ Koranne RV, Sachdeva KG (1988). "Vitiligo". Int J Dermatol. 27 (10): 676–81. PMID 3069756.
- ↑ Goldman L, Moraites RS, Kitzmiller KW (1966). "White spots in biblical times. A background for the dermatologist for participation in discussions of current revisions of the bible". Arch Dermatol. 93 (6): 744–53. PMID 5326716.
- ↑ Kopera D (1997). "Historical aspects and definition of vitiligo". Clin Dermatol. 15 (6): 841–3. PMID 9404686.
- ↑ 5.0 5.1 Millington GW, Levell NJ (2007). "Vitiligo: the historical curse of depigmentation". Int J Dermatol. 46 (9): 990–5. doi:10.1111/j.1365-4632.2007.03195.x. PMID 17822509.
- ↑ LERNER AB (1959). "Vitiligo". J Invest Dermatol. 32 (2, Part 2): 285–310. PMID 13641799.