Vitiligo natural history, complications and prognosis: Difference between revisions
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==Natural History== | ==Natural History== | ||
* The natural history of vitiligo is uncertain.<ref name="pmid21839315">{{cite journal| author=Alikhan A, Felsten LM, Daly M, Petronic-Rosic V| title=Vitiligo: a comprehensive overview Part I. Introduction, epidemiology, quality of life, diagnosis, differential diagnosis, associations, histopathology, etiology, and work-up. | journal=J Am Acad Dermatol | year= 2011 | volume= 65 | issue= 3 | pages= 473-91 | pmid=21839315 | doi=10.1016/j.jaad.2010.11.061 | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=21839315 }} </ref> | * The natural history of vitiligo is uncertain.<ref name="pmid21839315">{{cite journal| author=Alikhan A, Felsten LM, Daly M, Petronic-Rosic V| title=Vitiligo: a comprehensive overview Part I. Introduction, epidemiology, quality of life, diagnosis, differential diagnosis, associations, histopathology, etiology, and work-up. | journal=J Am Acad Dermatol | year= 2011 | volume= 65 | issue= 3 | pages= 473-91 | pmid=21839315 | doi=10.1016/j.jaad.2010.11.061 | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=21839315 }} </ref> | ||
* Approximately half of the cases present before the age of 20. | * Approximately half of the cases present before the age of 20 years. | ||
* The onset is acute and starts with a rapid loss of pigmentation in sun-exposed and friction areas, most commonly face and extremities. | * The onset is acute and starts with a rapid loss of pigmentation in sun-exposed and friction areas, most commonly face and extremities. | ||
* A latent period can occur, but remission is uncommon. | * A latent period can occur, but remission is uncommon. | ||
Revision as of 20:44, 25 June 2014
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Overview
The natural history of vitiligo is not well defined. The disease is unpredictable and there is no definitive treatment. Depigmentation may be stable or progressive and can cause even a total body depigmentation or remit spontaneously, although spontaneous remission is uncommon.
Natural History
- The natural history of vitiligo is uncertain.[1]
- Approximately half of the cases present before the age of 20 years.
- The onset is acute and starts with a rapid loss of pigmentation in sun-exposed and friction areas, most commonly face and extremities.
- A latent period can occur, but remission is uncommon.
Prognosis
- It is difficult to predict the progression and outcome of vitiligo
- Some markers of poor prognosis have been identified:[2]
- Family history
- Mucosal involvement or mucosal vitiligo
- Koebner phenomenon
- Nonsegmental vitiligo
References
- ↑ Alikhan A, Felsten LM, Daly M, Petronic-Rosic V (2011). "Vitiligo: a comprehensive overview Part I. Introduction, epidemiology, quality of life, diagnosis, differential diagnosis, associations, histopathology, etiology, and work-up". J Am Acad Dermatol. 65 (3): 473–91. doi:10.1016/j.jaad.2010.11.061. PMID 21839315.
- ↑ Dave S, Thappa DM, Dsouza M (2002). "Clinical predictors of outcome in vitiligo". Indian J Dermatol Venereol Leprol. 68 (6): 323–5. PMID 17656989.