Pancuronium

Pancuronium
Black Box Warning
Adult Indications & Dosage
Pediatric Indications & Dosage
Contraindications
Warnings & Precautions
Adverse Reactions
Drug Interactions
Use in Specific Populations
Administration & Monitoring
Overdosage
Pharmacology
Clinical Studies
How Supplied
Images
Patient Counseling Information
Precautions with Alcohol
Brand Names
Look-Alike Names

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Chetan Lokhande, M.B.B.S [2]

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Black Box Warning

Black Box warning See full prescribing information for complete Boxed Warning. Condition Name: THIS DRUG SHOULD BE ADMINISTERED BY ADEQUATELY TRAINED INDIVIDUALS FAMILIAR WITH ITS ACTIONS, CHARACTERISTICS, AND HAZARDS.

Overview

Pancuronium is a skeletal muscle relaxant and neuromuscular blocking drugs that is FDA approved for the {{{indicationType}}} of general anesthesia; adjunct. There is a Black Box Warning for this drug as shown here. Common adverse reactions include musculoskeletal: prolonged neuromuscular block.

Adult Indications and Dosage

FDA-Labeled Indications and Dosage (Adult)

• Dosage must be individualized
• General anesthesia; Adjunct: initial, 0.04 to 0.1 mg/kg IV (endotracheal intubation, 0.06 to 0.1 mg/kg IV); later incremental doses starting at 0.01 mg/kg may be used

Off-Label Use and Dosage (Adult)

Guideline-Supported Use

There is limited information regarding Off-Label Guideline-Supported Use of Pancuronium in adult patients.

Non–Guideline-Supported Use

There is limited information regarding Off-Label Non–Guideline-Supported Use of Pancuronium in adult patients.

Pediatric Indications and Dosage

FDA-Labeled Indications and Dosage (Pediatric)

Dosage must be individualized General anesthesia; Adjunct: (all ages except neonates) initial, 0.04 to 0.1 mg/kg IV (endotracheal intubation, 0.06 to 0.1 mg/kg IV); later incremental doses starting at 0.01 mg/kg may be used [2] General anesthesia; Adjunct: (neonates) administer a test dose of 0.02 mg/kg IV to measure responsiveness

Off-Label Use and Dosage (Pediatric)

Guideline-Supported Use

There is limited information regarding Off-Label Guideline-Supported Use of Pancuronium in pediatric patients.

Non–Guideline-Supported Use

There is limited information regarding Off-Label Non–Guideline-Supported Use of Pancuronium in pediatric patients.

Contraindications

There is limited information regarding Pancuronium Contraindications in the drug label.

Warnings

Black Box warning See full prescribing information for complete Boxed Warning. Condition Name: THIS DRUG SHOULD BE ADMINISTERED BY ADEQUATELY TRAINED INDIVIDUALS FAMILIAR WITH ITS ACTIONS, CHARACTERISTICS, AND HAZARDS.

There is limited information regarding Pancuronium Warnings' in the drug label.

Adverse Reactions

Clinical Trials Experience

There is limited information regarding Pancuronium Clinical Trials Experience in the drug label.

Postmarketing Experience

There is limited information regarding Pancuronium Postmarketing Experience in the drug label.

Drug Interactions

There is limited information regarding Pancuronium Drug Interactions in the drug label.

Use in Specific Populations

Pregnancy

Pregnancy Category (FDA): There is no FDA guidance on usage of Pancuronium in women who are pregnant.
Pregnancy Category (AUS): There is no Australian Drug Evaluation Committee (ADEC) guidance on usage of Pancuronium in women who are pregnant.

Labor and Delivery

There is no FDA guidance on use of Pancuronium during labor and delivery.

Nursing Mothers

There is no FDA guidance on the use of Pancuronium in women who are nursing.

Pediatric Use

There is no FDA guidance on the use of Pancuronium in pediatric settings.

Geriatic Use

There is no FDA guidance on the use of Pancuronium in geriatric settings.

Gender

There is no FDA guidance on the use of Pancuronium with respect to specific gender populations.

Race

There is no FDA guidance on the use of Pancuronium with respect to specific racial populations.

Renal Impairment

There is no FDA guidance on the use of Pancuronium in patients with renal impairment.

Hepatic Impairment

There is no FDA guidance on the use of Pancuronium in patients with hepatic impairment.

Females of Reproductive Potential and Males

There is no FDA guidance on the use of Pancuronium in women of reproductive potentials and males.

Immunocompromised Patients

There is no FDA guidance one the use of Pancuronium in patients who are immunocompromised.

Administration and Monitoring

Administration

There is limited information regarding Pancuronium Administration in the drug label.

Monitoring

There is limited information regarding Pancuronium Monitoring in the drug label.

IV Compatibility

There is limited information regarding the compatibility of Pancuronium and IV administrations.

Overdosage

There is limited information regarding Pancuronium overdosage. If you suspect drug poisoning or overdose, please contact the National Poison Help hotline (1-800-222-1222) immediately.

Pharmacology

There is limited information regarding Pancuronium Pharmacology in the drug label.

Mechanism of Action

There is limited information regarding Pancuronium Mechanism of Action in the drug label.

Structure

There is limited information regarding Pancuronium Structure in the drug label.

Pharmacodynamics

There is limited information regarding Pancuronium Pharmacodynamics in the drug label.

Pharmacokinetics

There is limited information regarding Pancuronium Pharmacokinetics in the drug label.

Nonclinical Toxicology

There is limited information regarding Pancuronium Nonclinical Toxicology in the drug label.

Clinical Studies

There is limited information regarding Pancuronium Clinical Studies in the drug label.

How Supplied

There is limited information regarding Pancuronium How Supplied in the drug label.

Storage

There is limited information regarding Pancuronium Storage in the drug label.

Images

Drug Images

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Package and Label Display Panel

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Patient Counseling Information

There is limited information regarding Pancuronium Patient Counseling Information in the drug label.

Precautions with Alcohol

Alcohol-Pancuronium interaction has not been established. Talk to your doctor about the effects of taking alcohol with this medication.

Brand Names

There is limited information regarding Pancuronium Brand Names in the drug label.

Look-Alike Drug Names

There is limited information regarding Pancuronium Look-Alike Drug Names in the drug label.

Drug Shortage Status

Price

References

The contents of this FDA label are provided by the National Library of Medicine.