Leprosy natural history, complications and prognosis: Difference between revisions
Jump to navigation
Jump to search
Joao Silva (talk | contribs) |
Joao Silva (talk | contribs) |
||
| Line 8: | Line 8: | ||
Worldwide, 1-2 million persons are permanently disabled as a result of leprosy:<ref name="WalkerLockwood2007">{{cite journal|last1=Walker|first1=Stephen L.|last2=Lockwood|first2=Dina N.J.|title=Leprosy|journal=Clinics in Dermatology|volume=25|issue=2|year=2007|pages=165–172|issn=0738081X|doi=10.1016/j.clindermatol.2006.05.012}}</ref> The number and degree of [[complications]] will depend on how early the condition is [[diagnosed]] and [[therapy|treatment]] is started. The later a correct [[diagnosis]] is reached, greater the number and the severity of the [[complications]]. These may include: | Worldwide, 1-2 million persons are permanently disabled as a result of leprosy:<ref name="WalkerLockwood2007">{{cite journal|last1=Walker|first1=Stephen L.|last2=Lockwood|first2=Dina N.J.|title=Leprosy|journal=Clinics in Dermatology|volume=25|issue=2|year=2007|pages=165–172|issn=0738081X|doi=10.1016/j.clindermatol.2006.05.012}}</ref> The number and degree of [[complications]] will depend on how early the condition is [[diagnosed]] and [[therapy|treatment]] is started. The later a correct [[diagnosis]] is reached, greater the number and the severity of the [[complications]]. These may include: | ||
* Cosmetic disfigurement with [[skin ulceration]] and [[scars]]. | * Cosmetic disfigurement with [[skin ulceration]] and [[scars]]. | ||
* Permanent [[nerve damage]], with [[sensory loss]] and [[numbness]], particularly in around [[skin lesions]]. | * Permanent [[nerve damage]], with [[sensory loss]] and [[numbness]], particularly in around [[skin lesions]]. | ||
* [[Muscle weakness]] | * [[Muscle weakness]] | ||
* [[ | |||
* [[Contractures]] | |||
* [[Blindness]] - due to the [[nerve damage]], conditions such as [[corneal abrasion]] and [[corneal ulceration]] may occur, potentially leading to [[blindness]]<ref name="pmid16707521">{{cite journal| author=Daniel E, Ffytche TJ, Kempen JH, Rao PS, Diener-West M, Courtright P| title=Incidence of ocular complications in patients with multibacillary leprosy after completion of a 2 year course of multidrug therapy. | journal=Br J Ophthalmol | year= 2006 | volume= 90 | issue= 8 | pages= 949-54 | pmid=16707521 | doi=10.1136/bjo.2006.094870 | pmc=PMC1857220 | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=16707521 }} </ref> | |||
* [[Burns]] and [[trauma]] - attending to the [[loss of sensation]], following the [[nerve damage]] caused by this condition, a potential [[complication]] is the non voluntary self-inflicted [[trauma]] as a result of the absence of [[pain]]. | * [[Burns]] and [[trauma]] - attending to the [[loss of sensation]], following the [[nerve damage]] caused by this condition, a potential [[complication]] is the non voluntary self-inflicted [[trauma]] as a result of the absence of [[pain]]. | ||
* [[Infection]] - following painless [[injuries]], due to the [[nerve damage]], that become [[infected]] by [[bacteria]] and complicate. | * [[Infection]] - following painless [[injuries]], due to the [[nerve damage]], that become [[infected]] by [[bacteria]] and complicate. | ||
* Thick and [[dry skin]] | |||
==Prognosis== | ==Prognosis== | ||
Revision as of 22:49, 4 July 2014
|
Leprosy Microchapters |
|
Diagnosis |
|---|
|
Treatment |
|
Case Studies |
|
Leprosy natural history, complications and prognosis On the Web |
|
American Roentgen Ray Society Images of Leprosy natural history, complications and prognosis |
|
Leprosy natural history, complications and prognosis in the news |
|
Blogs on Leprosy natural history, complications and prognosis |
|
Risk calculators and risk factors for Leprosy natural history, complications and prognosis |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: João André Alves Silva, M.D. [2]
Natural History
Complications
Worldwide, 1-2 million persons are permanently disabled as a result of leprosy:[1] The number and degree of complications will depend on how early the condition is diagnosed and treatment is started. The later a correct diagnosis is reached, greater the number and the severity of the complications. These may include:
- Cosmetic disfigurement with skin ulceration and scars.
- Permanent nerve damage, with sensory loss and numbness, particularly in around skin lesions.
- Blindness - due to the nerve damage, conditions such as corneal abrasion and corneal ulceration may occur, potentially leading to blindness[2]
- Burns and trauma - attending to the loss of sensation, following the nerve damage caused by this condition, a potential complication is the non voluntary self-inflicted trauma as a result of the absence of pain.
- Infection - following painless injuries, due to the nerve damage, that become infected by bacteria and complicate.
- Thick and dry skin
Prognosis
Early recognition is important. Early treatment limits damage by the disease, renders the person noninfectious, and allows for a normal lifestyle.
References
- ↑ Walker, Stephen L.; Lockwood, Dina N.J. (2007). "Leprosy". Clinics in Dermatology. 25 (2): 165–172. doi:10.1016/j.clindermatol.2006.05.012. ISSN 0738-081X.
- ↑ Daniel E, Ffytche TJ, Kempen JH, Rao PS, Diener-West M, Courtright P (2006). "Incidence of ocular complications in patients with multibacillary leprosy after completion of a 2 year course of multidrug therapy". Br J Ophthalmol. 90 (8): 949–54. doi:10.1136/bjo.2006.094870. PMC 1857220. PMID 16707521.