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{{WBRQuestion
{{WBRQuestion
|QuestionAuthor={{Rim}}
|QuestionAuthor={{Rim}} {{Alison}}
|ExamType=USMLE Step 1
|ExamType=USMLE Step 1
|MainCategory=Microbiology
|MainCategory=Microbiology
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|MainCategory=Microbiology
|MainCategory=Microbiology
|SubCategory=Genitourinary
|SubCategory=Genitourinary
|Prompt=A 38 year old Caucasian male presents to the emergency department with fever and back pain that radiates to the inguinal area.  Vital signs reveal a temperature of 38.5 degrees C (101 degrees F), heart rate of 98 beats per minute, and blood pressure measuring 122/88 mmHg.  After appropriate work-up, the diagnosis of struvite stone is made.  Stone culture and urine culture are performed; they reveal urea-splitting organism with swarming motility.  What other characteristics does this organism have?
|Prompt=A 38-year-old male presents to the ER with complaints of fever and back pain, radiating to the inguinal area.  Vital signs reveal a temperature of 38.5 °C, heart rate of 98 beats per minute, and blood pressure measuring 122/88 mmHg.  Following appropriate work-up, you diagnose him with struvite stone and preform a stone and urine culture.  The cultures reveal a urea-splitting organism with swarming motility.  Which of the following characteristics most likely corresponds to this organism?
|Explanation=Proteus mirabilis is a common causative agent of struvite stones.  It is an oxidase-negative, catalase-positive, urease-positive organism.  It has a characteristic “swarming” motility in cultures.  It is a known pathogen of the urogenital tract.  Proteus is considered a urea-splitting organism, similar to Pseudomonas, Klebsiella, Staphylococcus, and Mycoplasma.
|Explanation=''Proteus mirabilis'', a causative agent of struvite stones, is an oxidase-negative, catalase-positive, urease-positive organism, which has a characteristic “swarming” motility in cultures.  ''Proteus mirabilis'' is a known pathogen of the urogenital tract.  Other examples of urea-splitting organisms are ''Pseudomonas'', ''Klebsiella'', ''Staphylococcus'', and ''Mycoplasma''.


Educational Objective:
|EducationalObjectives=
Proteus mirabilis is a common causative agent of struvite stones.  It is an oxidase-negative, catalase-positive, urease-positive organism with characteristic “swarming” motility.
|''Proteus mirabilis'' is a common causative agent of struvite stones.  It is an oxidase-negative, catalase-positive, urease-positive organism with characteristic “swarming” motility.


|AnswerA=Oxidase-positive, catalase-positive, urease-positive
|AnswerA=Oxidase-positive, catalase-positive, urease-positive
|AnswerAExp=Proteus is not oxidase-positive.
|AnswerAExp=''Proteus mirabilis'' is not oxidase-positive.
|AnswerB=Oxidase-negative, catalase-negative, urease-positive
|AnswerB=Oxidase-negative, catalase-negative, urease-positive
|AnswerBExp=Proteus is not catalase-positive
|AnswerBExp=''Proteus mirabilis'' is not catalase-positive.
|AnswerC=Oxidase-positive, catalase-negative, urease-negative
|AnswerC=Oxidase-positive, catalase-negative, urease-negative
|AnswerCExp=Proteus is none of the findings in option C.
|AnswerCExp=''Proteus mirabilis'' is not oxidase-positive, catalase-negative, nor urease-negative.
|AnswerD=Oxidase-negative, catalase-positive, urease-positive
|AnswerD=Oxidase-negative, catalase-positive, urease-positive
|AnswerDExp=Proteus mirabilis is correctly an oxidase-negative, catalase-positive, urease-positive organism  
|AnswerDExp=''Proteus mirabilis'' is correctly an oxidase-negative, catalase-positive, urease-positive organism.
|AnswerE=Oxidase-positive, catalase-positive, urease-negative
|AnswerE=Oxidase-positive, catalase-positive, urease-negative
|AnswerEExp=Proteus is not oxidase positive and not urease-negative.
|AnswerEExp=''Proteus mirabilis'' is not oxidase positive nor urease-negative.
|RightAnswer=D
|RightAnswer=D
|Approved=No
|Approved=Yes
}}
}}

Revision as of 18:37, 16 July 2014

 
Author [[PageAuthor::Rim Halaby, M.D. [1] (Reviewed by Alison Leibowitz)]]
Exam Type ExamType::USMLE Step 1
Main Category MainCategory::Microbiology
Sub Category SubCategory::Genitourinary
Prompt [[Prompt::A 38-year-old male presents to the ER with complaints of fever and back pain, radiating to the inguinal area. Vital signs reveal a temperature of 38.5 °C, heart rate of 98 beats per minute, and blood pressure measuring 122/88 mmHg. Following appropriate work-up, you diagnose him with struvite stone and preform a stone and urine culture. The cultures reveal a urea-splitting organism with swarming motility. Which of the following characteristics most likely corresponds to this organism?]]
Answer A AnswerA::Oxidase-positive, catalase-positive, urease-positive
Answer A Explanation AnswerAExp::''Proteus mirabilis'' is not oxidase-positive.
Answer B AnswerB::Oxidase-negative, catalase-negative, urease-positive
Answer B Explanation AnswerBExp::''Proteus mirabilis'' is not catalase-positive.
Answer C AnswerC::Oxidase-positive, catalase-negative, urease-negative
Answer C Explanation AnswerCExp::''Proteus mirabilis'' is not oxidase-positive, catalase-negative, nor urease-negative.
Answer D AnswerD::Oxidase-negative, catalase-positive, urease-positive
Answer D Explanation AnswerDExp::''Proteus mirabilis'' is correctly an oxidase-negative, catalase-positive, urease-positive organism.
Answer E AnswerE::Oxidase-positive, catalase-positive, urease-negative
Answer E Explanation AnswerEExp::''Proteus mirabilis'' is not oxidase positive nor urease-negative.
Right Answer RightAnswer::D
Explanation [[Explanation::Proteus mirabilis, a causative agent of struvite stones, is an oxidase-negative, catalase-positive, urease-positive organism, which has a characteristic “swarming” motility in cultures. Proteus mirabilis is a known pathogen of the urogenital tract. Other examples of urea-splitting organisms are Pseudomonas, Klebsiella, Staphylococcus, and Mycoplasma.

Educational Objective:
References: ]]

Approved Approved::Yes
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