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{{WBRQuestion
{{WBRQuestion
|QuestionAuthor={{Rim}}
|QuestionAuthor={{Rim}} {{Alison}}
|ExamType=USMLE Step 1
|ExamType=USMLE Step 1
|MainCategory=Physiology
|MainCategory=Physiology
Line 20: Line 20:
|MainCategory=Physiology
|MainCategory=Physiology
|SubCategory=Renal
|SubCategory=Renal
|Prompt=A researcher is studying the role of aldosterone at the level of renal tubules.  He conducts an experiment whereby he measures urinary concentration of sodium, potassium, and hydrogen before and after aldosterone administration.  With respect to urinary concentrations before the administration of aldosterone, which of the following parameters is true for concentrations of urinary sodium, potassium, and hydrogen (in order) after aldosterone administration?
|Prompt=A researcher, studying the role of aldosterone at the level of renal tubules, measures the urinary concentration of sodium, potassium, and hydrogen before and after aldosterone administration.  With respect to urinary concentrations before the administration of aldosterone, which of the following parameters is true for concentrations of urinary sodium, potassium, and hydrogen (in order) following aldosterone administration?
[[Image:Urinary Electrolytes Aldosteron WBR.png|600px]]
[[Image:Urinary Electrolytes Aldosteron WBR.png|600px]]
|Explanation=Aldosterone accelerates the ion exchange of sodium for potassium or hydrogen.  Aldosterone acts at the level of collecting ducts to reabsorb sodium, and excrete potassium and hydrogen.  Thus, urinary concentrations of sodium will be decreased, while urinary concentrations of potassium and hydrogen will be increased.
|Explanation=[[Aldosterone]] accelerates the ion exchange of sodium for potassium and hydrogen.  [[Aldosterone]] acts at the level of collecting ducts to reabsorb sodium, and excrete potassium and hydrogen.  Thus, urinary concentrations of sodium will decrease, while urinary concentrations of potassium and hydrogen will increase.


Educational Objective:
|EducationalObjectives= [[Aldosterone]], which acts on the renal collecting tubule, accelerates the ion exchange of sodium for potassium and hydrogen, allowing for the increased reabsorption of sodium and excretion of both potassium and hydrogen.
Aldosterone acts on the renal collecting tubule.  It accelerates the ion exchange of sodium for potassium or hydrogen; allowing increased reabsorption of sodium and excretion of both potassium and hydrogen.
|References= First Aid 2014 page 318
|AnswerA=Increased - Decreased - Decreased
 
|AnswerAExp=An increase in sodium, accompanied by a decrease in potassium and hydrogen, is seen in the serum, not in urine.
|AnswerA=Increased - Decreased - Decreased
|AnswerB=Increased - Increased - Decreased
|AnswerAExp=An increase in sodium, accompanied by a decrease in potassium and hydrogen, occurs in the serum, not in urine.
|AnswerBExp=Following aldosterone administration, urinary sodium is decreased due to aldsoterone’s activity in reabsorbing sodium, and urinary hydrogen is increased due to aldosterone’s activity in excreting hydrogen.
|AnswerB=Increased - Increased - Decreased
|AnswerBExp=Following [[aldosterone]] administration, urinary sodium is decreased due to the reabsorption of sodium and urinary hydrogen is increased due to the excretion of hydrogen.
|AnswerC=Decreased - Increased - Increased
|AnswerC=Decreased - Increased - Increased
|AnswerCExp=Aldosterone accelerates the ion exchange of sodium for potassium or hydrogen; allowing increased reabsorption of sodium and excretion of both potassium and hydrogen.
|AnswerCExp=[[Aldosterone]] accelerates the ion exchange of sodium for potassium or hydrogen, increasing the reabsorption of sodium and the excretion of both potassium and hydrogen.
|AnswerD=Decreased - Increased - Unchanged
|AnswerD=Decreased - Increased - Unchanged
|AnswerDExp=Following aldosterone administration, hydrogen is excreted.  Its urinary concentration will be increased. It will not remain unchanged.
|AnswerDExp=Following [[aldosterone]] administration, hydrogen is excreted into the urine.
|AnswerE=Decreased - Decreased - Increased
|AnswerE=Decreased - Decreased - Increased
|AnswerEExp=Following aldosterone administration, urinary potassium increases, while serum potassium is decreased due to aldosterone’s activity in excreting potassium.
|AnswerEExp=Following [[aldosterone]] administration, urinary potassium increases and serum potassium decreases due to the excretion of potassium.
|RightAnswer=C
|RightAnswer=C
|Approved=No
|Approved=Yes
}}
}}

Revision as of 13:35, 17 July 2014

 
Author [[PageAuthor::Rim Halaby, M.D. [1] (Reviewed by Alison Leibowitz)]]
Exam Type ExamType::USMLE Step 1
Main Category MainCategory::Physiology
Sub Category SubCategory::Renal
Prompt [[Prompt::A researcher, studying the role of aldosterone at the level of renal tubules, measures the urinary concentration of sodium, potassium, and hydrogen before and after aldosterone administration. With respect to urinary concentrations before the administration of aldosterone, which of the following parameters is true for concentrations of urinary sodium, potassium, and hydrogen (in order) following aldosterone administration?

]]

Answer A AnswerA::Increased - Decreased - Decreased
Answer A Explanation AnswerAExp::An increase in sodium, accompanied by a decrease in potassium and hydrogen, occurs in the serum, not in urine.
Answer B AnswerB::Increased - Increased - Decreased
Answer B Explanation [[AnswerBExp::Following aldosterone administration, urinary sodium is decreased due to the reabsorption of sodium and urinary hydrogen is increased due to the excretion of hydrogen.]]
Answer C AnswerC::Decreased - Increased - Increased
Answer C Explanation [[AnswerCExp::Aldosterone accelerates the ion exchange of sodium for potassium or hydrogen, increasing the reabsorption of sodium and the excretion of both potassium and hydrogen.]]
Answer D AnswerD::Decreased - Increased - Unchanged
Answer D Explanation [[AnswerDExp::Following aldosterone administration, hydrogen is excreted into the urine.]]
Answer E AnswerE::Decreased - Decreased - Increased
Answer E Explanation [[AnswerEExp::Following aldosterone administration, urinary potassium increases and serum potassium decreases due to the excretion of potassium.]]
Right Answer RightAnswer::C
Explanation [[Explanation::Aldosterone accelerates the ion exchange of sodium for potassium and hydrogen. Aldosterone acts at the level of collecting ducts to reabsorb sodium, and excrete potassium and hydrogen. Thus, urinary concentrations of sodium will decrease, while urinary concentrations of potassium and hydrogen will increase.

Educational Objective: Aldosterone, which acts on the renal collecting tubule, accelerates the ion exchange of sodium for potassium and hydrogen, allowing for the increased reabsorption of sodium and excretion of both potassium and hydrogen.
References: First Aid 2014 page 318]]

Approved Approved::Yes
Keyword
Linked Question Linked::
Order in Linked Questions LinkedOrder::