Sandbox JA: Difference between revisions
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* Presence of latent [[spores]] must be taken into account when selecting postexposure [[prophylaxis]] or a combination of [[antibiotics]] for treatment of [[anthrax]]. | * Presence of latent [[spores]] must be taken into account when selecting postexposure [[prophylaxis]] or a combination of [[antibiotics]] for treatment of [[anthrax]]. | ||
Hospitalized patients for systemic [[anthrax]] should be immediately treated with a combination of [[broad-spectrum]] [[intravenous]] [[antimicrobial drug]] treatment pending confirmatory test results because any delay may prove fatal. | Hospitalized patients for systemic [[anthrax]] should be immediately treated with a combination of [[broad-spectrum]] [[intravenous]] [[antimicrobial drug]] treatment pending confirmatory test results because any delay may prove fatal. | ||
Because meningitis and hemorrhagic brain parenchymal infection was observed in ≤50% of cases, meningitis must be considered in all cases of systemic anthrax. therefore antibiotics to treat possible meningitis must have good penetration of the central nervous system (CNS). | |||
==Antimicrobial Treatment== | ==Antimicrobial Treatment== | ||
Revision as of 14:33, 17 July 2014
Medical Therapy
The treatment of anthrax infection includes antimicrobial and antitoxin agents. This treatment and postexposure prophylaxis differs from other bacterial infections because:
- Production of toxin
- Potential antibiotic resistance
- Frequent occurrence of meningitis
- Presence of latent spores must be taken into account when selecting postexposure prophylaxis or a combination of antibiotics for treatment of anthrax.
Hospitalized patients for systemic anthrax should be immediately treated with a combination of broad-spectrum intravenous antimicrobial drug treatment pending confirmatory test results because any delay may prove fatal.
Because meningitis and hemorrhagic brain parenchymal infection was observed in ≤50% of cases, meningitis must be considered in all cases of systemic anthrax. therefore antibiotics to treat possible meningitis must have good penetration of the central nervous system (CNS).