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Well-timed and effective PEP can potentially save thousands of lives. PEP of asymptomatic persons should ideally start as soon as possible after exposure because its effectiveness decreases with delay in implementation. After exposure to anthrax, it is recommended 60 days of antimicrobial drug prophylaxis for immediate protection and a 3-dose series of Anthrax Vaccine Adsorbed (AVA)  for long-term protection.<ref name="pmid20651644">{{cite journal| author=Wright JG, Quinn CP, Shadomy S, Messonnier N, Centers for Disease Control and Prevention (CDC)| title=Use of anthrax vaccine in the United States: recommendations of the Advisory Committee on Immunization Practices (ACIP), 2009. | journal=MMWR Recomm Rep | year= 2010 | volume= 59 | issue= RR-6 | pages= 1-30 | pmid=20651644 | doi= | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=20651644  }} </ref>
Well-timed and effective postexposure prophylaxis can potentially save thousands of lives. PEP of asymptomatic persons should ideally start as soon as possible after exposure because its effectiveness decreases with delay in implementation. After exposure to anthrax, it is recommended 60 days of antimicrobial drug prophylaxis for immediate protection and a 3-dose series of Anthrax Vaccine Adsorbed (AVA)  for long-term protection.<ref name="pmid20651644">{{cite journal| author=Wright JG, Quinn CP, Shadomy S, Messonnier N, Centers for Disease Control and Prevention (CDC)| title=Use of anthrax vaccine in the United States: recommendations of the Advisory Committee on Immunization Practices (ACIP), 2009. | journal=MMWR Recomm Rep | year= 2010 | volume= 59 | issue= RR-6 | pages= 1-30 | pmid=20651644 | doi= | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=20651644  }} </ref> To ensure adequate and continued protection, everyone exposed to aerosolized B. anthracis spores should receive a full 60 days of PEP antimicrobial drugs, whether they are unvaccinated, partially vaccinated, or fully vaccinated.<ref name=CDC>{{cite web | title = Centers for Disease Control and Prevention Expert Panel Meetings on Prevention and Treatment of Anthrax in Adults | url = http://wwwnc.cdc.gov/eid/article/20/2/13-0687_article }}</ref>

Revision as of 18:28, 17 July 2014

Well-timed and effective postexposure prophylaxis can potentially save thousands of lives. PEP of asymptomatic persons should ideally start as soon as possible after exposure because its effectiveness decreases with delay in implementation. After exposure to anthrax, it is recommended 60 days of antimicrobial drug prophylaxis for immediate protection and a 3-dose series of Anthrax Vaccine Adsorbed (AVA) for long-term protection.[1] To ensure adequate and continued protection, everyone exposed to aerosolized B. anthracis spores should receive a full 60 days of PEP antimicrobial drugs, whether they are unvaccinated, partially vaccinated, or fully vaccinated.[2]

  1. ↑ Wright JG, Quinn CP, Shadomy S, Messonnier N, Centers for Disease Control and Prevention (CDC) (2010). "Use of anthrax vaccine in the United States: recommendations of the Advisory Committee on Immunization Practices (ACIP), 2009". MMWR Recomm Rep. 59 (RR-6): 1–30. PMID 20651644.
  2. ↑ "Centers for Disease Control and Prevention Expert Panel Meetings on Prevention and Treatment of Anthrax in Adults".
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