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| __NOTOC__
| | #REDIRECT [[Cholestyramine]] |
| {{Cholestyramine}}
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| {{CMG}}; {{AE}} {{SS}}
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| ==Drug Interactions==
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| Cholestyramine resin may delay or reduce the absorption of concomitant oral medication such as [[phenylbutazone]], [[warfarin]],[[ thiazide diuretics]] ([[acidic]]), or [[propranolol]] (basic), as well as [[tetracycline]], [[penicillin G]], [[phenobarbital]], thyroid and thyroxine preparations, [[estrogen]]s and [[progestin]]s, and [[digitalis]]. Interference with the absorption of oral phosphate supplements has been observed with another positively-charged bile acid sequestrant. Cholestyramine resin may interfere with the pharmacokinetics of drugs that undergo enterohepatic circulation. The discontinuance of cholestyramine resin could pose a hazard to health if a potentially toxic drug such as [[digitalis]] has been titrated to a maintenance level while the patient was taking cholestyramine resin.
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| Because cholestyramine binds bile acids, cholestyramine resin may interfere with normal fat digestion and absorption and thus may prevent absorption of fat-soluble vitamins such as A, D, E and K. When cholestyramine resin is given for long periods of time, concomitant supplementation with water-miscible (or parenteral) forms of fat-soluble vitamins should be considered.
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| '''SINCE CHOLESTYRAMINE RESIN MAY BIND OTHER DRUGS GIVEN CONCURRENTLY, IT IS RECOMMENDED THAT PATIENTS TAKE OTHER DRUGS AT LEAST ONE HOUR BEFORE OR 4 TO 6 HOURS AFTER PREVALITE® (OR AT AS GREAT AN INTERVAL AS POSSIBLE) TO AVOID IMPEDING THEIR ABSORPTION.'''<ref name="dailymed.nlm.nih.gov">{{Cite web | last = | first = | title = PREVALITE (CHOLESTYRAMINE) POWDER, FOR SUSPENSION [UPSHER-SMITH LABORATORIES INC.] | url = http://dailymed.nlm.nih.gov/dailymed/lookup.cfm?setid=dd434ef8-8af3-434c-a0a0-9a0b18459ba0 | publisher = | date = | accessdate = 10 February 2014 }}</ref>
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| ==References==
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| {{Reflist|2}}
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| {{Lipid modifying agents}}
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| [[Category:Hepatology]]
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| [[Category:Bile acid sequestrants]]
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| [[Category:Cardiovasuclar Drugs]]
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| [[Category:Drugs]]
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