Lovastatin overdosage: Difference between revisions

Revision as of 14:07, 21 July 2014

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+#redirect [[Lovastatin#Overdosage]]
-{{Lovastatin}}
-{{CMG}}; {{AE}} {{SS}}
-==Overdosage==
-After oral administration of lovastatin immediate-release to mice the median lethal dose observed was >15 g/m2.
-Five healthy human volunteers have received up to 200 mg of lovastatin as a single dose without clinically significant adverse experiences. A few cases of accidental overdosage with lovastatin immediate-release have been reported; no patients had any specific symptoms, and all patients recovered without sequelae. The maximum dose taken was 5 g to 6 g.
-Until further experience is obtained, no specific treatment of overdosage with Altoprev® can be recommended.
-The dialyzability of lovastatin and its metabolites in man is not known at present.<ref name="dailymed.nlm.nih.gov">{{Cite web  | last =  | first =  | title = ALTOPREV (LOVASTATIN) TABLET, EXTENDED RELEASE [SHIONOGI INC.] | url = http://dailymed.nlm.nih.gov/dailymed/lookup.cfm?setid=e8b6ccc2-e6e7-45fd-ab66-c312bcbe2b01 | publisher =  | date =  | accessdate = 13 February 2014 }}</ref>
-==References==
-{{Reflist|2}}
-{{Statins}}
 [[Category:Statins]]
 [[Category:Carboxylate esters]]
 [[Category:Lactones]]
-[[Category:Cardiovascular Drug]]
+[[Category:Cardiovascular Drugs]]
 [[Category:Drug]]