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| __NOTOC__
| | #REDIRECT [[Rosuvastatin#Structure]] |
| {{Rosuvastatin}}
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| {{CMG}}; {{AE}} {{SS}}
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| ==Description==
| | [[Category: Cardiovascular Drugs]] |
| CRESTOR (rosuvastatin calcium) is a synthetic lipid-lowering agent for oral administration.
| | [[Category: Drug]] |
| | | [[Category: Statins]] |
| The chemical name for rosuvastatin calcium is bis[(E)-7-[4-(4-fluorophenyl)-6-isopropyl-2-[methyl(methylsulfonyl)amino] pyrimidin-5-yl](3R,5S)-3,5-dihydroxyhept-6-enoic acid] calcium salt with the following structural formula:
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| {|
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| |[[File:Rosuvastatin04.jpg|thumb|800px]]
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| {|
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| |[[File:Rosuvastatin3Dan.gif|thumb|800px]]
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| The empirical formula for rosuvastatin calcium is (C22H27FN3O6S)2Ca and the molecular weight is 1001.14. Rosuvastatin calcium is a white amorphous powder that is sparingly soluble in water and methanol, and slightly soluble in ethanol. Rosuvastatin calcium is a hydrophilic compound with a partition coefficient (octanol/water) of 0.13 at pH of 7.0.
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| CRESTOR Tablets for oral administration contain 5, 10, 20, or 40 mg of rosuvastatin and the following inactive ingredients: Each tablet contains: microcrystalline cellulose NF, lactose monohydrate NF, tribasic calcium phosphate NF, crospovidone NF, magnesium stearate NF, hypromellose NF, triacetin NF, titanium dioxide USP, yellow ferric oxide, and red ferric oxide NF.<ref name="dailymed.nlm.nih.gov">{{Cite web | last = | first = | title = CRESTOR (ROSUVASTATIN CALCIUM) TABLET, FILM COATED [ASTRAZENECA PHARMACEUTICALS LP] | url = http://dailymed.nlm.nih.gov/dailymed/lookup.cfm?setid=bb0f3b5e-4bc6-41c9-66b9-6257e2513512 | publisher = | date = | accessdate = 17 February 2014 }}</ref>
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| ==References==
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| {{Reflist|2}}
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| {{statins}}
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| [[Category:Statins]] | |
| [[Category:Quinolines]] | |
| [[Category:Diols]] | |
| [[Category:Carboxylic acids]]
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| [[Category:Organofluorides]]
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| [[Category:Cyclopropanes]]
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| [[Category:Cardiovascular Drugs]]
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| [[Category:Drugs]]
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