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| __NOTOC__
| | #REDIRECT [[Flecainide#Nonclinical Toxicology]] |
| {{Flecainide}}
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| {{CMG}}; {{AE}} {{SS}}
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| ==Nonclinical Toxicology==
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| '''Carcinogenesis, Mutagenesis, Impairment of Fertility'''. Long-term studies with flecainide in rats and mice at doses up to 60 mg/kg/day have not revealed any compound-related carcinogenic effects. Mutagenicity studies (Ames test, mouse lymphoma and in vivo cytogenetics) did not reveal any mutagenic effects. A rat reproduction study at doses up to 50 mg/kg/day (seven times the usual human dose) did not reveal any adverse effect on male or female fertility.<ref name="dailymed.nlm.nih.gov">{{Cite web | last = | first = | title = FLECAINIDE ACETATE TABLET [APOTEX CORP.] | url = http://dailymed.nlm.nih.gov/dailymed/lookup.cfm?setid=72595783-e6a0-6b7a-f428-9ca03d707794#nlm34084-4 | publisher = | date = | accessdate = 11 March 2014 }}</ref>
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| ==References==
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| {{Reflist}}
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| [[Category:Antiarrhythmic agents]]
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| [[Category:Piperidines]]
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| [[Category:Benzamides]]
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| [[Category:Phenol ethers]]
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| [[Category:Organofluorides]]
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| [[Category:Sodium channel blockers]]
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| [[Category:Cardiovascular Drugs]]
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| [[Category:Drugs]]
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