Mexiletine nonclinical toxicology: Difference between revisions

Latest revision as of 21:54, 21 July 2014

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+#REDIRECT [[Mexiletine#Nonclinical Toxicology]]
-{{Mexiletine}}
-{{CMG}}; {{AE}} {{SS}}
-==Nonclinical Toxicology==
-Carcinogenesis, Mutagenesis, Impairment of Fertility
-Studies of carcinogenesis in rats (24 months) and mice (18 months) did not demonstrate any tumorigenic potential. Mexiletine was found to be non-mutagenic in the Ames test. Mexiletine did not impair fertility in the rat.<ref name="dailymed.nlm.nih.gov">{{Cite web  | last =  | first =  | title = MEXILETINE HYDROCHLORIDE CAPSULE [TEVA PHARMACEUTICALS USA INC] | url = http://dailymed.nlm.nih.gov/dailymed/lookup.cfm?setid=693da40b-26d4-40d6-87d1-158e256f40ab | publisher =  | date =  | accessdate = 3 March 2014 }}</ref>
-==References==
-{{Reflist}}
-{{Antiarrhythmic agents}}
-[[Category:Sodium channel blockers]]
-[[Category:Phenol ethers]]
-[[Category:Cardiovascular Drugs]]
-[[Category:Drugs]]