Isosorbide dinitrate description: Difference between revisions

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#REDIRECT [[Isosorbide dinitrate#Pharmacology]]
{{Isosorbide dinitrate}}
{{CMG}}; {{AE}} {{PB}}
 
==Description==
Isosorbide dinitrate (ISDN) is 1,4:3,6-dianhydro-D-glucitol 2,5-dinitrate, an organic nitrate whose structural formula is:
 
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and whose molecular weight is 236.14. The organic nitrates are vasodilators, active on both arteries and veins.
 
Isosorbide dinitrate is a white, crystalline, odorless compound which is stable in air and in solution, has a melting point of 70°C and has an optical rotation of +134° (c=1.0, alcohol, 20°C). Isosorbide dinitrate is freely soluble in organic solvents such as acetone, alcohol, and ether, but is only sparingly soluble in water.
 
Each Isordil<sup>®</sup> Titradose™ tablet contains 5 or 40 mg of isosorbide dinitrate. The inactive ingredients in each tablet are lactose, cellulose, and magnesium stearate. The 5 mg and 40 mg dosage strengths also contain the following: 5 mg – FD&C Red 40; 40 mg – D&C Yellow 10, FD&C Blue 1, and FD&C Yellow 6.<ref name="dailymed.nlm.nih.gov">{{Cite web  | last =  | first =  | title = ISORDIL (ISOSORBIDE DINITRATE) TABLET [BTA PHARMACEUTICALS, INC.] | url = http://dailymed.nlm.nih.gov/dailymed/lookup.cfm?setid=abb3ad49-73a8-49c5-adc5-164d052971d7 | publisher =  | date =  | accessdate = 30 January 2014 }}</ref>
==References==
 
{{Reflist|2}}
 
[[Category:Drugs]]

Latest revision as of 22:39, 21 July 2014