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| __NOTOC__
| | #REDIRECT [[Guanfacine#Overdosage]] |
| {{Guanfacine}}
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| {{CMG}}; {{AE}} {{SS}}
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| ==Overdosage==
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| ===Symptoms===
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| Post-marketing reports of guanfacine overdosage indicate that [[hypotension]], [[drowsiness]], [[lethargy]], and [[bradycardia]] have been observed following overdose. Initial [[hypertension]] may develop early and may be followed by [[hypotension]]. Similar symptoms have been described in voluntary reports to the American Association of Poison Control Center’s National Poison Data System. Miosis of the pupils may be noted on examination. No fatal overdoses of guanfacine have been reported in published literature.
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| ===Treatment===
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| Consult a Certified Poison Control Center by calling 1-800-222-1222 for up to date guidance and advice.
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| Management of INTUNIV® overdose should include monitoring for and the treatment of initial [[hypertension]], if that occurs, as well as [[hypotension]], [[bradycardia]], lethargy and respiratory depression. Children and adolescents who develop lethargy should be observed for the development of more serious toxicity including coma, [[bradycardia]] and [[hypotension]] for up to 24 hours, due to the possibility of delayed onset [[hypotension]].<ref name="dailymed.nlm.nih.gov">{{Cite web | last = | first = | title = INTUNIV (GUANFACINE) TABLET, EXTENDED RELEASE INTUNIV (GUANFACINE) KIT [SHIRE US MANUFACTURING INC.] | url = http://dailymed.nlm.nih.gov/dailymed/lookup.cfm?setid=b972af81-3a37-40be-9fe1-3ddf59852528#section-12.1 | publisher = | date = | accessdate = 25 February 2014 }}</ref>
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| ==References==
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| {{reflist|2}}
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| {{Antihypertensives and diuretics}}
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| {{Antihyperkinetics}}
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| {{Adrenergics}}
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| [[Category:Antihypertensive agents]]
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| [[Category:Guanidines]]
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| [[Category:Alpha-adrenergic agonists]]
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| [[Category:Acetamides]]
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| [[Category:Organochlorides]]
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| [[Category:Cardiovascular Drugs]]
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| [[Category:Drugs]]
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