Gitoformate: Difference between revisions

Jump to navigation Jump to search
VisualWikitext
m (Robot: Automated text replacement (-{{SIB}} + & -{{EH}} + & -{{EJ}} + & -{{Editor Help}} + & -{{Editor Join}} +))
No edit summary
Line 27: Line 27:
{{CMG}}
{{CMG}}


==Overview==
'''Gitoformate''' ([[International Nonproprietary Name|INN]], or '''pentaformylgitoxin''', trade name '''Dynocard''') is a [[cardiac glycoside]], a type of drug that can be used in the treatment of [[congestive heart failure]] and [[cardiac arrhythmia]] (irregular heartbeat).<ref>{{cite pmid|6541927}}</ref> Produced by [[Madaus]], it is not available in the US, and does not seem to be available in Europe either.


==Chemistry==


Gitoformate is a derivative of the [[glycoside]] gitoxin, with five of the six free [[hydroxyl]] groups [[formyl]]ated, one on the [[aglycon]] and four on the sugar.<ref>{{cite pmid|6542412}}</ref><ref>{{PubChem|91540}}</ref> Gitoxin, a cardiac glycoside from the Woolly Foxglove (''Digitalis lanata''), has an aglycon of the [[cardenolide]] type named gitoxigenin, which is also the aglycon of lanatoside B, another ''Digitalis lanata'' glycoside.<ref>{{cite book|authors=William O. Foye,Thomas L. Lemke, David A. Williams|title=Foye's principles of medicinal chemistry|page=699|isbn=978-0-7817-6879-5}}</ref>


==[[Gitoformate (patient information)|For patient information, click here]]==
==References==
 
{{reflist|2}}
==Overview==
'''Gitoformate''' (or '''pentaformylgitoxin''') is a [[cardiac glycoside]].
 


{{Cardiac glycosides}}
{{Cardiac glycosides}}


[[Category:Cardiac glycosides]]
[[Category:Cardiovascular Drugs]]
[[Category:Drugs]]
[[Category:Drugs]]


{{WikiDoc Help Menu}}
{{WikiDoc Help Menu}}
{{WikiDoc Sources}}
{{WikiDoc Sources}}

Revision as of 15:37, 23 July 2014

Gitoformate
Clinical data
ATC code
Identifiers
CAS Number
PubChem CID
E number{{#property:P628}}
ECHA InfoCard{{#property:P2566}}Lua error in Module:EditAtWikidata at line 36: attempt to index field 'wikibase' (a nil value).
Chemical and physical data
FormulaC46H64O19
Molar mass920.989 g/mol

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Overview

Gitoformate (INN, or pentaformylgitoxin, trade name Dynocard) is a cardiac glycoside, a type of drug that can be used in the treatment of congestive heart failure and cardiac arrhythmia (irregular heartbeat).[1] Produced by Madaus, it is not available in the US, and does not seem to be available in Europe either.

Chemistry

Gitoformate is a derivative of the glycoside gitoxin, with five of the six free hydroxyl groups formylated, one on the aglycon and four on the sugar.[2][3] Gitoxin, a cardiac glycoside from the Woolly Foxglove (Digitalis lanata), has an aglycon of the cardenolide type named gitoxigenin, which is also the aglycon of lanatoside B, another Digitalis lanata glycoside.[4]

References

  1. ↑ PMID 6541927 (PMID 6541927)
    Citation will be completed automatically in a few minutes. Jump the queue or expand by hand
  2. ↑ PMID 6542412 (PMID 6542412)
    Citation will be completed automatically in a few minutes. Jump the queue or expand by hand
  3. ↑ Template:PubChem
  4. ↑ William O. Foye,Thomas L. Lemke, David A. Williams. Foye's principles of medicinal chemistry. p. 699. ISBN 978-0-7817-6879-5.

Template:Cardiac glycosides


Template:WikiDoc Sources

Retrieved from "https://www.wikidoc.org/index.php?title=Gitoformate&oldid=999564"