Gitoformate

Gitoformate

Clinical data
ATC code	C01AA09 (WHO)
Identifiers
CAS Number	10176-39-3
PubChem CID	65598
E number	{{#property:P628}}
ECHA InfoCard	{{#property:P2566}}
Chemical and physical data
Formula	C46H64O19
Molar mass	920.989 g/mol

WikiDoc Resources for Gitoformate
Articles
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Evidence Based Medicine
Cochrane Collaboration on Gitoformate Bandolier on Gitoformate TRIP on Gitoformate
Clinical Trials
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Commentary
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Definitions
Definitions of Gitoformate
Patient Resources / Community
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Healthcare Provider Resources
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Continuing Medical Education (CME)
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Experimental / Informatics
List of terms related to Gitoformate

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Overview

Gitoformate (INN, or pentaformylgitoxin, trade name Dynocard) is a cardiac glycoside, a type of drug that can be used in the treatment of congestive heart failure and cardiac arrhythmia (irregular heartbeat). Produced by Madaus, it is not available in the US, and does not seem to be available in Europe either.

Chemistry

Gitoformate is a derivative of the glycoside gitoxin, with five of the six free hydroxyl groups formylated, one on the aglycon and four on the sugar. Gitoxin, a cardiac glycoside from the Woolly Foxglove (Digitalis lanata), has an aglycon of the cardenolide type named gitoxigenin, which is also the aglycon of lanatoside B, another Digitalis lanata glycoside.