WBR0608
| Author | [[PageAuthor::Yazan Daaboul, M.D. (Reviewed by Yazan Daaboul, M.D. and Alison Leibowitz [1])]] |
|---|---|
| Exam Type | ExamType::USMLE Step 1 |
| Main Category | MainCategory::Immunology, MainCategory::Microbiology |
| Sub Category | SubCategory::General Principles |
| Prompt | [[Prompt::A young boy is brought by his mother to the physician's office for a scheduled vaccination. The boy has no complaints, and physical examination is unremarkable. Prior to the administration of the vaccine, the mother asks the physician if the vaccine is associated with any serious adverse reactions. The physician explains that the child may experience a self-resolving low-grade fever or rash within the 7 to 21 days following administration of the vaccine. Which of the following vaccines is the child most likely receiving during his check-up?
Which of the following is an inactivated/killed vaccine?]] |
| Answer A | AnswerA::Oral polio vaccine (OPV) |
| Answer A Explanation | AnswerAExp::This is a live, attenuated vaccine. |
| Answer B | AnswerB::Measles, mumps, and rubella (MMR) vaccine |
| Answer B Explanation | AnswerBExp::This is a live, attenuated vaccine. |
| Answer C | AnswerC::Tetanus-diphtheria (Td) vaccine |
| Answer C Explanation | AnswerCExp::This is an example of a toxoid or inactivated toxin. |
| Answer D | AnswerD::Human papillomavirus (HPV) |
| Answer D Explanation | AnswerDExp::This belongs to the group subunit/conjugate type i.e., they are prepared using a protein subunit of the microorganism or using a poorly immunogenic polysaccharide capsule. |
| Answer E | AnswerE::Hepatitis A vaccine |
| Answer E Explanation | AnswerEExp::This is an example of an inactivated or heat killed vaccine. |
| Right Answer | RightAnswer::E |
| Explanation | [[Explanation::Vaccines may be categorized as follows:
A vaccine is a biological preparation that establishes immunity to a particular disease. A vaccine typically contains an agent that resembles a pathogen and is often made from an inactivated or killed form of the microorganism, its toxins, or surface proteins. The agent stimulates the body's immune system to recognize the agent as foreign, destroy it, and keep a record of it, so that in the future, when the pathogen enters the body the immune response is expedited. There are four major types of vaccines:
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| Approved | Approved::No |
| Keyword | WBRKeyword::Live vaccines, WBRKeyword::killed vaccines |
| Linked Question | Linked:: |
| Order in Linked Questions | LinkedOrder:: |
