Enterovirus 68 historical perspective
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
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Overview
Human enterovirus 68 (EV-D68) was initially detected in 1962 from samples of 4 children presenting for pneumonia and bronchiolitis at a hospital in California. It is a rare disease that has only become more evident in the past decade. The most recent outbreak occured in September 2014 at involved 10 states including Colorado, North Carolina, Georgia, Ohio, Iowa, Illinois, Missouri, Kansas, Oklahoma and Kentucky.
Historical Perspective
Human enterovirus 68 (EV-D68) was initially detected in 1962 from samples of 4 children presenting for pneumonia and bronchiolitis at a hospital in California.[1] Prior to 2005, reports of enterovirus 68 infections were very limited. Only 26 cases of verified EV-D68 infection were documented between 1970 and 2005. This represents 0.1% of all enterovirus isolates in that time frame, one of the rarest infectious enteroviruses. Over the past couple of years, outbreaks of EV-D68 have been documented in Japan, the Philippines and the Netherlands, as well as several clusters in the USA.[2] The most recent of these outbreaks occurred in late August and September of 2014 with clusters reported in 10 states including Colorado, North Carolina, Georgia, Ohio, Iowa, Illinois, Missouri, Kansas, Oklahoma and Kentucky.
References
- ↑ Schieble, JH.; Fox, VL.; Lennette, EH. (1967). "A probable new human picornavirus associated with respiratory diseases". Am J Epidemiol. 85 (2): 297–310. PMID 4960233. Unknown parameter
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ignored (help) - ↑ Tokarz R, Firth C, Madhi SA, Howie SR, Wu W, Sall AA; et al. (2012). "Worldwide emergence of multiple clades of enterovirus 68". J Gen Virol. 93 (Pt 9): 1952–8. doi:10.1099/vir.0.043935-0. PMC 3542132. PMID 22694903.