WBR0502

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Author [[PageAuthor::Ayokunle Olubaniyi, M.B,B.S [1]]]
Exam Type ExamType::USMLE Step 1
Main Category MainCategory::Behavioral Science/Psychiatry
Sub Category SubCategory::Endocrine
Prompt [[Prompt::A 7-year-old boy is brought to the pediatrics clinic for fever of 39 °C (102.2 °F), cough, and wheezing for the past week. Over the last 24 hours, the child has developed nausea, vomiting, and watery diarrhea. The child's past medical history is significant for neurofibromatosis, asthma, and seizure disorder. He is currently taking daily albuterol and valproic acid. His mother explains that she was diagnosed with insulin-dependent diabetes mellitus at his age and fears he may have developed it too. On physical examination, you note a lethargic and ill-appearing boy. His heart rate is 96/min, blood pressure is 124/84 mm Hg, temperature is 36.8°C (98.2°F), and respiratory rate is 28/min. You decide to admit the child for evaluation and monitoring. Over the next two days, the patient has recurrent episodes of hypoglycemia, with fingerstick glucose levels as low as 33 mg/dL. Both episodes occur at night, with the mother alerting the nurses each time. Further investigation reveals a serum insulin level of 2344 µU/mL (5–25 µU/mL) and a C-peptide level of 0.7 ng/mL (0.8–4.0 ng/mL). What is the most likely diagnosis in this patient?]]
Answer A AnswerA::Insulinoma
Answer A Explanation AnswerAExp::
Answer B AnswerB::Sulfonylurea intake
Answer B Explanation AnswerBExp::
Answer C AnswerC::Exogenous insulin administration
Answer C Explanation AnswerCExp::
Answer D AnswerD::Type 1 diabetes mellitus
Answer D Explanation AnswerDExp::
Answer E AnswerE::Adrenal insufficiency
Answer E Explanation AnswerEExp::
Right Answer RightAnswer::C
Explanation [[Explanation::

Educational Objective:
References: ]]

Approved Approved::Yes
Keyword WBRKeyword::Insulin, WBRKeyword::Insulinoma, WBRKeyword::Munchausen's syndrome by proxy, WBRKeyword::Hypoglycemia, WBRKeyword::C-peptide
Linked Question Linked::
Order in Linked Questions LinkedOrder::