Hydroa vacciniforme-like lymphoma other diagnostic studies
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Jesus Rosario Hernandez, M.D. [2] Alberto Plate [3]
Histology
Histology of the affected area commonly shows dense perivascular lymphocytic infiltration with reticulated degeneration of the epidermis. A study by Iwatsuki et al. detected Epstein-Barr virus (EBV) positive T-cells in the perivascular infiltration on biopsy in 28/29 patients tested. Antibody titers to EBV were measured in 14 of these patients and only five had abnormal antibody patterns consistent with chronic active EBV infection.[1]
References
- ↑ Iwatsuki, K; Satoh M; Yamamoto T; Oono T; Morizane S; Ohtsuka M; Xu ZG; Suzuki D; Tsuji K (2006). "Pathogenic link between hydroa vacciniforme and Epstein-Barr virus-associated hematologic disorders". Arch Dermatol. May;142(5): 587–95.