List of chemotherapeutic agents
Template:Seealso Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Aparna Vuppala, M.B.B.S. [2]; Steven Bellm, M.D. [3]
Overview
This is a list of chemotherapeutic agents that are known to be of use in chemotherapy for cancer. A full alphabetical listing is included after the categorical listing.
The agents in this list are often combined into chemotherapy regimens for polychemotherapy (combination chemotherapy).
Chemotherapeutic Agents by Category
Alkylating agents
Nitrogen mustards
- Chlorambucil (Leukeran)
- Cyclophosphamide (Cytoxan)
- Estramustine (Emcyt)
- Ifosfamide (Iflex)
- Melphalan (Alkeran)
- Mechlorethamine (Mustargen)
Ethylenimines
Methylhydrazines
Alkylsulfonates
Nitrosoureas
Triazenes
Platinum coordination complexes
Antimetabolites
Folic acid analogs
Pyrimidine analogs
- Azacytidine (Vidaza)
- Capecitabine (Xeloda)
- Cytarabine (Cytosar)
- Decitabine (Dacogen)
- Floxuridine (FUDR)
- Fluorouracil (Adrucil, Efudex)
- Gemcitabine (Gemzar)
- Raltitrexed (Tomudex)
Purine analogs
- Cladribine (Leustatin)
- Clofarabine (Clolar)
- Fludarabine (Fludara)
- Mercaptopurine (Purinethol)
- Nelarabine (Arranon)
- Pentostatin (Nipent)
- Thioguanine (Tabloid)
Ribonucleotide reductase inhibitors
Natural products
Vinca alkaloids
- Vinblastine (Velban, Velsar)
- Vincristine (Oncovin, Vincasar)
- Vincristine liposome (Marqibo)
- Vinflunine (Javlor)
- Vinorelbine (Navelbine)
Taxanes
Epipodophyllotoxins
Camptothecins/Topoisomerase inhibitors
Antineoplastic antibiotics
- Bleomycin (Blenoxane)
- Dactinomycin (Cosmegen)
- Daunorubicin (Cerubidine)
- Daunorubicin liposome (Daunoxome)
- Doxorubicin (Adriamycin, Rubex)
- Epirubicin (Ellence)
- Idarubicin (Idamycin)
- Mitomycin C (Mutamycin)
- Mitoxantrone (Novantrone)
- Valrubicin (Valstar)
Antineoplastic enzymes
Hormones and Antagonists
Adrenocortical suppressants
Glucocorticoids
Progestins
Anti-estrogens
Aromatase inhibitors
Androgens
Anti-androgens
- Abarelix (Plenaxis)
- Abiraterone (Zytiga)
- Bicalutamide (Casodex)
- Enzalutamide (Xtandi)
- Flutamide (Eulexin)
- Nilutamide (Nilandron)
LHRH agonists
GnRH agonists
GnRH antagonists
Biologics
Monoclonal antibodies
Anti-CD3 antibodies
Anti-CD3 & anti-CD19 antibodies
Anti-CD20 antibodies
- Rituximab (Rituxan)
- Ibritumomab (Zevalin)
- Obinutuzumab (Gazyva)
- Ofatumumab (Arzerra)
- Tositumomab (Bexxar)
Anti-CD30 antibodies
Anti-CD33 antibodies
Anti-CD52 antibodies
Anti-CTLA–4 antibodies
Anti-EGFR (ErbB1) antibodies
Anti-PD–1 antibodies
Anti-HER2/neu (ErbB2) antibodies
Anti-VEGF antibodies
IL-2 inhibitors
IL-6 inhibitors
Immunotherapy
Hematopoietic Growth Factors
Erythrocyte growth factors
Granulocyte growth factors
Megakaryocyte growth factors
Supportive Medications
Chemotherapy protective agents
- Amifostine (Ethyol)
- Cyanocobalamin (Cobal)
- Dexrazoxane (Zinecard)
- Folinic acid (Leucovorin)
- Glucarpidase (Voraxaze)
- Levoleucovorin (Fusilev)
- Mesna (Mesnex)
- Rasburicase (Elitek)
Antiemetic agents
RANK ligand inhibitors
Miscellaneous
Mitotic inhibitors
Bisphosphonates
HDAC inhibitors
Hedgehog pathway inhibitors
Immunomodulatory drugs (IMiDs)
Kinase inhibitors
- Afatinib (Gliotrif)
- Axitinib (Inlyta)
- Bosutinib (Bosulif)
- Cabozantinib (Cometriq)
- Ceritinib (Zykadia)
- Crizotinib (Xalkori)
- Dabrafenib (Tafinlar)
- Dasatinib (Sprycel)
- Erlotinib (Tarceva)
- Gefitinib (Iressa)
- Ibrutinib (Imbruvica)
- Idelalisib (Zydelig)
- Lapatinib (Tykerb)
- Nilotinib (Tasigna)
- Palbociclib (Ibrance)
- Regorafenib (Stivarga)
- Ruxolitinib (Jakafi)
- Sorafenib (Nexavar)
- Sunitinib (Sutent)
- Trametinib (Mekinist)
- Vandetanib (Caprelsa)
- Vemurafenib (Zelboraf)
- Ziv-aflibercept (Zaltrap)
mTOR Inhibitors
Photosensitizing agents
Proteasome inhibitors
Radioactive agents
Somatostatin analogs
Differentiating agents
Chemotherapeutic Agents in Alphabetical Order
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